The Role of Dopamine in the Collective Regulation of Foraging in Harvester Ants.
The Role of Dopamine in the Collective Regulation of Foraging in Harvester Ants.
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DOI：
10.1016/j.isci.2018.09.001
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发表时间：
2018-10-26
期刊：
影响因子：
5.8
通讯作者：
Gordon DM
中科院分区：
文献类型：
--
作者：
Friedman DA;Pilko A;Skowronska-Krawczyk D;Krasinska K;Parker JW;Hirsh J;Gordon DM
红收获蚁（Pogonomyrmex vanatus）的殖民地不同，他们如何调节集体觅食活动，以应对湿度的变化。我们使用转录组学，生理学和药理学实验来研究这种生态学上重要的群体行为变异的分子基础。觅食动物脑组织的RNA测序表明，群体觅食活动和生物胺和神经激素代谢和信号相关的转录本的差异表达之间存在关联。在野外实验中，觅食动物脑多巴胺滴度的药理学增加引起觅食活动的显着增加。自然对湿度最敏感的殖民地对外源多巴胺的刺激作用反应更明显。此外，觅食脑组织中的生物胺含量显着不同的殖民地。与个体觅食者对湿度的敏感性相关的菌落之间的神经生理学变化可能反映了自然选择作用于塑造觅食的集体调节的遗传分子变化。红收获蚁群体在干燥条件下调整觅食努力的方式各不相同行为不同的群体在觅食者大脑转录组中存在显着差异多巴胺的药理学增加在野外实验中增加觅食来自对湿度更敏感的群体的觅食者更容易受到多巴胺的刺激昆虫学;神经科学;分子神经科学
Colonies of the red harvester ant (Pogonomyrmex barbatus) differ in how they regulate collective foraging activity in response to changes in humidity. We used transcriptomic, physiological, and pharmacological experiments to investigate the molecular basis of this ecologically important variation in collective behavior among colonies. RNA sequencing of forager brain tissue showed an association between colony foraging activity and differential expression of transcripts related to biogenic amine and neurohormonal metabolism and signaling. In field experiments, pharmacological increases in forager brain dopamine titer caused significant increases in foraging activity. Colonies that were naturally most sensitive to humidity were significantly more responsive to the stimulatory effect of exogenous dopamine. In addition, forager brain tissue significantly varied among colonies in biogenic amine content. Neurophysiological variation among colonies associated with individual forager sensitivity to humidity may reflect the heritable molecular variation on which natural selection acts to shape the collective regulation of foraging. Red harvester ant colonies vary in how they adjust foraging effort in dry conditions Colonies that differ in behavior significantly differ in forager brain transcriptome Pharmacological increases of dopamine increased foraging in field experiments Foragers from colonies more sensitive to humidity were more stimulated by dopamine Entomology; Neuroscience; Molecular Neuroscience
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影响因子：
5.2
作者：
Caers J;Verlinden H;Zels S;Vandersmissen HP;Vuerinckx K;Schoofs L
通讯作者：
Schoofs L
DOI：
10.1126/science.aar5723
发表时间：
2018-07-27
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Chandra V;Fetter-Pruneda I;Oxley PR;Ritger AL;McKenzie SK;Libbrecht R;Kronauer DJC
通讯作者：
Kronauer DJC
影响因子：
3
作者：
Davidson, Jacob D.;Arauco-Aliaga, Roxana P.;Goldman, Mark S.
通讯作者：
Goldman, Mark S.
DOI：
10.1111/j.2517-6161.1995.tb02031.x
发表时间：
1995-01-01
影响因子：
5.8
作者：
BENJAMINI, Y;HOCHBERG, Y
通讯作者：
HOCHBERG, Y
影响因子：
3.7
作者：
Costa-Silva J;Domingues D;Lopes FM
通讯作者：
Lopes FM