Boron nitride nanotubes are noncytotoxic and can be functionalized for interaction with proteins and cells.
Boron nitride nanotubes are noncytotoxic and can be functionalized for interaction with proteins and cells.
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DOI:
10.1021/ja807334b
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发表时间:
2009-01-28
影响因子:
15
通讯作者:
Bertozzi CR
中科院分区:
文献类型:
--
作者:
Chen X;Wu P;Rousseas M;Okawa D;Gartner Z;Zettl A;Bertozzi CR
We report the discovery that boron nitride nanotubes (BNNTs), isosteres of CNTs with unique physical properties, are inherently noncytotoxic. Furthermore, we developed a biomemetic coating strategy to interface BNNTs with proteins and cells. Finally, we showed that BNNTs can deliver DNA oligomers to the interior of cells with no apparent toxicity. This work suggests that BNNTs may be superior to CNTs for use as biological probes and in biomaterials.
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