Enabling accurate and early detection of recently emerged SARS-CoV-2 variants of concern in wastewater.
Enabling accurate and early detection of recently emerged SARS-CoV-2 variants of concern in wastewater.
复制标题
在废水中,可以准确和早期检测最近出现的SARS-COV-2变体。
DOI:
10.1038/s41467-023-38184-3
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发表时间:
2023-05-17
影响因子:
16.6
通讯作者:
Treangen TJ
中科院分区:
文献类型:
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作者:
Sapoval N;Liu Y;Lou EG;Hopkins L;Ensor KB;Schneider R;Stadler LB;Treangen TJ
As clinical testing declines, wastewater monitoring can provide crucial surveillance on the emergence of SARS-CoV-2 variant of concerns (VoCs) in communities. In this paper we present QuaID, a novel bioinformatics tool for VoC detection based on quasi-unique mutations. The benefits of QuaID are three-fold: (i) provides up to 3-week earlier VoC detection, (ii) accurate VoC detection (>95% precision on simulated benchmarks), and (iii) leverages all mutational signatures (including insertions & deletions). Sapoval et al. introduce QuaID, a bioinformatics tool for SARS-CoV-2 variant detection based on quasi-unique mutations. QuaID leverages all mutations, including insertions and deletions, and provides precise detection of variants early in their spread.
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影响因子:
12.8
作者:
Brunner, F. S.;Brown, M. R.;Bassano, I;Denise, H.;Khalifa, M. S.;Wade, M. J.;van Aerle, R.;Kevill, J. L.;Jones, D. L.;Farkas, K.;Jeffries, A. R.;Cairns, E.;Wierzbicki, C.;Paterson, S.
通讯作者:
Paterson, S.
影响因子:
16.6
作者:
Smyth DS;Trujillo M;Gregory DA;Cheung K;Gao A;Graham M;Guan Y;Guldenpfennig C;Hoxie I;Kannoly S;Kubota N;Lyddon TD;Markman M;Rushford C;San KM;Sompanya G;Spagnolo F;Suarez R;Teixeiro E;Daniels M;Johnson MC;Dennehy JJ
通讯作者:
Dennehy JJ
影响因子:
30.8
作者:
Turakhia, Yatish;Thornlow, Bryan;Hinrichs, Angie S.;De Maio, Nicola;Gozashti, Landen;Lanfear, Robert;Haussler, David;Corbett-Detig, Russell
通讯作者:
Corbett-Detig, Russell
影响因子:
5.8
作者:
Huang, Weichun;Li, Leping;Marth, Gabor T.
通讯作者:
Marth, Gabor T.
影响因子:
28.3
作者:
通讯作者:
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