Body mass index and timing of pubertal initiation in boys.
Body mass index and timing of pubertal initiation in boys.
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DOI：
10.1001/archpediatrics.2009.258
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发表时间：
2010-02
影响因子：
--
通讯作者：
Lumeng, Julie C.
中科院分区：
文献类型：
--
作者：
Lee, Joyce M.;Kaciroti, Niko;Appugliese, Danielle;Corwyn, Robert F.;Bradley, Robert H.;Lumeng, Julie C.
在以人口为基础的美国男孩样本中，研究体重指数（BMI[以体重公斤除以身高米的平方计算]）与青春期开始时间之间的关系。纵向前瞻性研究。10个美国网站参与了国家儿童健康和人类发展研究所的早期儿童护理和青少年发展研究。在最初参加研究的705名男孩中，有401名男孩的身高、体重和11.5岁前的青春期信息是可获得的。BMI轨迹是通过测量2岁、3岁、4.5岁、7岁、9岁、9.5岁、10.5岁和11.5岁时的身高和体重得出的。根据坦纳性器官分期，在11.5岁开始进入青春期。BMI轨迹最高的男孩（11.5岁时BMI z平均评分为1.84）比BMI轨迹最低的男孩（11.5岁时BMI z平均评分为- 0.76）发生青春期前的相对风险更高（调整后的相对风险=2.63；95%可信区间为1.05-6.61；P= 0.04）。体脂与青春期开始时间的关系在男孩和女孩中是不一样的。需要进一步的研究来更好地了解身体脂肪和两性青春期开始时间之间的生理联系。
To examine the association between body mass index (BMI [calculated as weight in kilograms divided by height in meters squared]) and timing of pubertal onset in a population-based sample of US boys. Longitudinal prospective study. Ten US sites that participated in the National Institute of Child Health and Human Development Study of Early Child Care and Youth Development. Of 705 boys initially enrolled in the study, information about height and weight measures and pubertal stage by age 11.5 years was available for 401 boys. The BMI trajectory created from measured heights and weights at ages 2, 3, 4.5, 7, 9, 9.5, 10.5, and 11.5 years. Onset of puberty at age 11.5 years as measured by Tanner genitalia staging. Boys in the highest BMI trajectory (mean BMI z score at age 11.5 years, 1.84) had a greater relative risk of being prepubertal compared with boys in the lowest BMI trajectory (mean BMI z score at age 11.5 years, −0.76) (adjusted relative risk=2.63; 95% confidence interval, 1.05–6.61; P=.04). The relationship between body fat and timing of pubertal onset is not the same in boys as it is in girls. Further studies are needed to better understand the physiological link between body fat and timing of pubertal onset in both sexes.
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影响因子：
3.2
作者：
Clayton, PE;Gill, MS;Price, DA
通讯作者：
Price, DA
影响因子：
5.8
作者：
Hayes, FJ;Seminara, SB;Crowley, WF
通讯作者：
Crowley, WF
影响因子：
5.1
作者：
MORRISON, JA;BARTON, B;OBARZANEK, E
通讯作者：
OBARZANEK, E
影响因子：
5.8
作者：
Mantzoros, CS;Flier, JS;Rogol, AD
通讯作者：
Rogol, AD
影响因子：
56.9
作者：
FRISCH, RE;MCARTHUR, JW
通讯作者：
MCARTHUR, JW