Identification and characterisation of 17 polymorphic candidate genes for response to parasitic nematode (Trichostrongylus tenuis) infection in red grouse (Lagopus lagopus scotica)

Identification and characterisation of 17 polymorphic candidate genes for response to parasitic nematode (Trichostrongylus tenuis) infection in red grouse (Lagopus lagopus scotica)
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红松鸡 (Lagopus lagopus scotica) 寄生线虫 (Trichostrongylus tenuis) 感染反应的 17 个多态性候选基因的鉴定和表征

DOI:
10.1007/s12686-014-0323-4
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发表时间:
2014
影响因子:
1.1
通讯作者:
Wenzel M
Wenzel M
中科院分区:
环境科学与生态学4区
文献类型:
--
作者:
Wenzel M

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红松鸡(Lagopus lagopus scotica)是一种重要的经济鸟类,产于不列颠群岛的高地石南荒原,由于繁殖种群的长期下降,其保护状况为“琥珀色”。松鸡种群生态的主要驱动因素之一是高度流行的胃肠道寄生线虫细毛圆线虫的慢性感染。在这里,我们概述了红松鸡对寄生虫感染生理反应的 17 个候选基因的鉴定和表征,这些基因是根据松鸡转录组和基因组资源的功能和遗传分析从头开发的。这些基因具有广泛的生理功能,包括免疫系统过程、外源物质解毒、氧化平衡、新陈代谢和细胞周期调节。所有基因在苏格兰东北部的景观尺度上都是多态性的,这表明对于描述与红松鸡种群中寄生虫介导的生态进化过程相关的时空遗传变异的原因和后果具有很大的实用性。
The red grouse (Lagopus lagopus scotica) is an economically important game bird species endemic to the upland heather moors of the British Isles, where its conservation status is “amber” due to long-term declines in breeding populations. One major driver of grouse population ecology is chronic infection by the highly prevalent, gastrointestinal parasitic nematodeTrichostrongylus tenuis. Here, we outline the identification and characterisation of 17 candidate genes for the physiological response of red grouse to parasite infection, developed de novo from functional and genetic analysis of grouse transcriptomic and genomic resources. These genes capture broad physiological functions, including immune system processes, xenobiotics detoxification, oxidative balance, metabolism and cell cycle regulation. All genes were polymorphic at the landscape scale in north-east Scotland, indicating great utility for characterising the causes and consequences of spatio-temporal genetic variation in relation to parasite-mediated eco-evolutionary processes in red grouse populations.
从红松鸡 Lagopus lagopus scoticus 的长期研究中洞察种群生态学。
DOI: 10.1111/1365-2656.12098
发表时间: 2014
期刊: The Journal of animal ecology
影响因子: --
作者:
Martínez-Padilla J
通讯作者: Martínez-Padilla J
DOI: 10.1093/bioinformatics/btp187
发表时间: 2009-06-01
期刊: BIOINFORMATICS
影响因子: 5.8
作者:
Librado, P.;Rozas, J.
通讯作者: Rozas, J.
DOI: 10.2307/4694
发表时间: 1986-02-01
影响因子: 4.8
作者:
HUDSON, PJ
通讯作者: HUDSON, PJ
DOI: 10.1017/s0031182000064817
发表时间: 1995-05-01
期刊: PARASITOLOGY
影响因子: 2.4
作者:
DELAHAY, RJ;SPEAKMAN, JR;MOSS, R
通讯作者: MOSS, R
红松鸡 (Lagopus lagopus scoticus) 中盲肠线虫 (Trichostrongylus tenuis) 的流行情况
DOI: --
发表时间: 1983
期刊: Oecologia
影响因子: 2.7
作者:
G. Wilson
通讯作者: G. Wilson