Identification and characterisation of 17 polymorphic candidate genes for response to parasitic nematode (Trichostrongylus tenuis) infection in red grouse (Lagopus lagopus scotica)
Identification and characterisation of 17 polymorphic candidate genes for response to parasitic nematode (Trichostrongylus tenuis) infection in red grouse (Lagopus lagopus scotica)
复制标题
红松鸡 (Lagopus lagopus scotica) 寄生线虫 (Trichostrongylus tenuis) 感染反应的 17 个多态性候选基因的鉴定和表征
DOI:
10.1007/s12686-014-0323-4
复制
发表时间:
2014
影响因子:
1.1
通讯作者:
Wenzel M
中科院分区:
文献类型:
--
作者:
Wenzel M
The red grouse (Lagopus lagopus scotica) is an economically important game bird species endemic to the upland heather moors of the British Isles, where its conservation status is “amber” due to long-term declines in breeding populations. One major driver of grouse population ecology is chronic infection by the highly prevalent, gastrointestinal parasitic nematodeTrichostrongylus tenuis. Here, we outline the identification and characterisation of 17 candidate genes for the physiological response of red grouse to parasite infection, developed de novo from functional and genetic analysis of grouse transcriptomic and genomic resources. These genes capture broad physiological functions, including immune system processes, xenobiotics detoxification, oxidative balance, metabolism and cell cycle regulation. All genes were polymorphic at the landscape scale in north-east Scotland, indicating great utility for characterising the causes and consequences of spatio-temporal genetic variation in relation to parasite-mediated eco-evolutionary processes in red grouse populations.
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DOI:
10.1111/1365-2656.12098
发表时间:
2014
期刊:
The Journal of animal ecology
影响因子:
--
作者:
Martínez-Padilla J
通讯作者:
Martínez-Padilla J
影响因子:
5.8
作者:
Librado, P.;Rozas, J.
通讯作者:
Rozas, J.
影响因子:
4.8
作者:
HUDSON, PJ
通讯作者:
HUDSON, PJ
影响因子:
2.4
作者:
DELAHAY, RJ;SPEAKMAN, JR;MOSS, R
通讯作者:
MOSS, R
影响因子:
2.7
作者:
G. Wilson
通讯作者:
G. Wilson