No association between fish intake and depression in over 15,000 older adults from seven low and middle income countries--the 10/66 study.

No association between fish intake and depression in over 15,000 older adults from seven low and middle income countries--the 10/66 study.
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DOI:
10.1371/journal.pone.0038879
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发表时间:
2012
期刊:
影响因子:
3.7
通讯作者:
Ferri CP
Ferri CP
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Albanese E;Lombardo FL;Dangour AD;Guerra M;Acosta D;Huang Y;Jacob KS;Llibre Rodriguez Jde J;Salas A;Schönborn C;Sosa AL;Williams J;Prince MJ;Ferri CP

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在低收入和中等收入国家,关于鱼类消费和抑郁症之间的联系的证据是不一致的,几乎不存在。使用标准方案,我们的目标是评估七个低收入和中等收入国家的鱼类消费与晚年抑郁之间的关系。我们使用了来自10/66队列研究的横断面数据,并应用了两个晚年抑郁症的诊断标准,根据ICD-10和EURO-D抑郁症症状量表评分来评估每周食用鱼类与抑郁症之间的关联,调整了相关的混杂因素。在古巴、多米尼加共和国、委内瑞拉、秘鲁、墨西哥、中国和印度进行了全流域调查,抽样调查了15,000多名社区居住的老年人(65岁以上)。使用泊松模型,调整后的鱼类消费类别与icd-10抑郁之间的关联在印度是正的(趋势 = 为0.001),在秘鲁为负(p = 0.025),在所有其他国家并不显著。我们发现,只有古巴(趋势 = 0.039)和中国(p<0.001)的鱼消费类别与EURO-D得分呈线性负相关;相关关系在所有其他国家并不显著。ICD-10(I2和GT;61%)和EURONE-D标准(I2和GT;66%)的国家间异质性显著。在大样本老年人中,食用鱼类与抑郁之间的联系在不同国家和抑郁症诊断中存在明显差异,并由社会人口和生活方式变量来解释。需要在这些环境中进行实验研究来证实我们的发现。
Evidence on the association between fish consumption and depression is inconsistent and virtually non-existent from low- and middle-income countries. Using a standard protocol, we aim to assess the association of fish consumption and late-life depression in seven low- and middle-income countries. We used cross-sectional data from the 10/66 cohort study and applied two diagnostic criteria for late-life depression to assess the association between categories of weekly fish consumption and depression according to ICD-10 and the EURO-D depression symptoms scale scores, adjusting for relevant confounders. All-catchment area surveys were carried out in Cuba, Dominican Republic, Venezuela, Peru, Mexico, China, and India, and over 15,000 community-dwelling older adults (65+) were sampled. Using Poisson models the adjusted association between categories of fish consumption and ICD-10 depression was positive in India (p for trend = 0.001), inverse in Peru (p = 0.025), and not significant in all other countries. We found a linear inverse association between fish consumption categories and EURO-D scores only in Cuba (p for trend  = 0.039) and China (p<0.001); associations were not significant in all other countries. Between-country heterogeneity was marked for both ICD-10 (I2>61%) and EURO-D criteria (I2>66%). The associations of fish consumption with depression in large samples of older adults varied markedly across countries and by depression diagnosis and were explained by socio-demographic and lifestyle variables. Experimental studies in these settings are needed to confirm our findings.
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发表时间: 2009-08
期刊: The American journal of clinical nutrition
影响因子: --
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Albanese E;Dangour AD;Uauy R;Acosta D;Guerra M;Guerra SS;Huang Y;Jacob KS;de Rodriguez JL;Noriega LH;Salas A;Sosa AL;Sousa RM;Williams J;Ferri CP;Prince MJ
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