Regulation of cholesterol biosynthesis and cancer signaling.
Regulation of cholesterol biosynthesis and cancer signaling.
复制标题
DOI:
10.1016/j.coph.2012.06.011
复制
发表时间:
2012-12
影响因子:
4
通讯作者:
Astsaturov, Igor
中科院分区:
文献类型:
--
作者:
Gorin, Andrey;Gabitova, Linara;Astsaturov, Igor
Cellular growth is highly dependent on sustained production of lipids. Sterol composition of cellular membranes determines multiple biochemical and biophysical properties of membrane-based processes including vesicle traffic, receptor signaling and assembly of protein complexes. Lipid biogenesis has become an attractive biochemical target in cancer given the high level of dependency on sterols and lipids in a cancer cell. This review summarized the current knowledge of mechanisms of interaction between the metabolism of sterols and receptor signaling.
登录
查看更多内容
DOI:
10.1126/science.1171396
发表时间:
2009-05-15
期刊:
Science (New York, N.Y.)
影响因子:
--
作者:
Fan HY;Liu Z;Shimada M;Sterneck E;Johnson PF;Hedrick SM;Richards JS
通讯作者:
Richards JS
影响因子:
8.8
作者:
Mashima, T.;Seimiya, H.;Tsuruo, T.
通讯作者:
Tsuruo, T.
影响因子:
4.6
作者:
Ma, Zhiguo;Liu, Zhonghua;Huang, Xun
通讯作者:
Huang, Xun
影响因子:
14.8
作者:
Burgett, Anthony W. G.;Poulsen, Thomas B.;Wangkanont, Kittikhun;Anderson, D. Ryan;Kikuchi, Chikako;Shimada, Kousei;Okubo, Shuichi;Fortner, Kevin C.;Mimaki, Yoshihiro;Kuroda, Minpei;Murphy, Jason P.;Schwalb, David J.;Petrella, Eugene C.;Cornella-Taracido, Ivan;Schirle, Markus;Tallarico, John A.;Shair, Matthew D.
通讯作者:
Shair, Matthew D.
影响因子:
11.2
作者:
Nagahashi M;Ramachandran S;Kim EY;Allegood JC;Rashid OM;Yamada A;Zhao R;Milstien S;Zhou H;Spiegel S;Takabe K
通讯作者:
Takabe K