Domestic infection of hepatitis E in Japan.
Domestic infection of hepatitis E in Japan.
复制标题
日本戊型肝炎国内感染。
作者：
M. Kumagai;Yutaka Nishii;Youichi Koizumi;Y. Akahane
在日本的大多数戊型肝炎病例中，患者是在国外戊型肝炎流行的国家感染病毒的。然而，在日本长野县，我们遇到了一位从未出过国的戊型肝炎患者。通过检测血清中戊型肝炎病毒RNA和抗病毒抗体进行诊断。肝功能检查迅速恢复正常，无需药物治疗。从该患者身上分离的病毒的核苷酸序列与之前分离的基因型III病毒的序列密切相关。无法确定感染源。
In most cases of hepatitis E in Japan, patients acquire the viral infection abroad in countries where hepatitis E is endemic. However, in Nagano Prefecture, Japan, we encountered a patient with hepatitis E who had never been abroad. The diagnosis was made on finding hepatitis E viral RNA and antibodies against the virus in the serum. Prompt normalization of liver function test occurred without medication. The nucleotide sequence of the virus isolated from this patient was closely related to the sequence of previously isolated viruses of genotype III. The source of infection could not be identified.
DOI：
10.4269/ajtmh.1999.61.331
发表时间：
1999-08-01
影响因子：
3.3
作者：
Kabrane-Lazizi, Y;Fine, JB;Purcell, RH
通讯作者：
Purcell, RH