Motility and more: the flagellum of Trypanosoma brucei.

Motility and more: the flagellum of Trypanosoma brucei.
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DOI:
10.1038/nrmicro3274
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发表时间:
2014-07
期刊:
Nature reviews. Microbiology
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A central feature of trypanosome cell biology and life cycle is the parasite’s single flagellum, which is an essential and multifunctional organelle involved in cell propulsion, morphogenesis and cytokinesis. The flagellar membrane is also a specialized subdomain of the cell surface that harbors multiple parasite virulence factors with roles in signaling and host-parasite interactions. In this review, we discuss the structure, assembly and function of the trypanosome flagellum, including canonical roles in cell motility as well as novel and emerging roles in cell morphogenesis and host-parasite interaction.
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