Design and synthesis of vidarabine prodrugs as antiviral agents.
Design and synthesis of vidarabine prodrugs as antiviral agents.
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DOI：
10.1016/j.bmcl.2008.12.031
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发表时间：
2009-02-01
影响因子：
2.7
通讯作者：
Hilfinger J
中科院分区：
文献类型：
--
作者：
Shen W;Kim JS;Kish PE;Zhang J;Mitchell S;Gentry BG;Breitenbach JM;Drach JC;Hilfinger J
5′-O-D- and L-amino acid derivatives and 5′-O-(D- and L-amino acid methyl ester phosphoramidate) derivatives of vidarabine (ara-A) were synthesized as vidarabine prodrugs. Some compounds were equi- or more potent in vitro than vidarabine against two pox viruses and their uptake by cultured cells was improved compared to the parent drug.
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影响因子：
1.8
作者：
JEKER, N;TAMM, C
通讯作者：
TAMM, C
影响因子：
11.5
作者：
Lea, AP;Bryson, HM
通讯作者：
Bryson, HM
影响因子：
4.9
作者：
SCHWARTZ, PM;SHIPMAN, C;DRACH, JC
通讯作者：
DRACH, JC
影响因子：
3.1
作者：
GLUSHKA, JN;PERLIN, AS
通讯作者：
PERLIN, AS
影响因子：
4.9
作者：
SHIPMAN, C;SMITH, SH;DRACH, JC
通讯作者：
DRACH, JC