Diagnosis for Latent Tuberculosis Infection: New Alternatives.
Diagnosis for Latent Tuberculosis Infection: New Alternatives.
复制标题
潜伏性结核感染的诊断:新的选择。
DOI:
10.3389/fimmu.2020.02006
复制
发表时间:
2020
影响因子:
7.3
通讯作者:
Torres M
中科院分区:
文献类型:
--
作者:
Carranza C;Pedraza-Sanchez S;de Oyarzabal-Mendez E;Torres M
Latent tuberculosis infection (LTBI) is a subclinical mycobacterial infection defined on the basis of cellular immune response to mycobacterial antigens. The tuberculin skin test (TST) and the interferon gamma release assay (IGRA) are currently used to establish the diagnosis of LTB. However, neither TST nor IGRA is useful to discriminate between active and latent tuberculosis. Moreover, these tests cannot be used to predict whether an individual with LTBI will develop active tuberculosis (TB) or whether therapy for LTBI could be effective to decrease the risk of developing active TB. Therefore, in this article, we review current approaches and some efforts to identify an immunological marker that could be useful in distinguishing LTBI from TB and in evaluating the effectiveness of treatment of LTB on the risk of progression to active TB.
登录
查看更多内容
影响因子:
3.7
作者:
Aggerbeck, Henrik;Giemza, Rafaela;Lewis, David J. M.
通讯作者:
Lewis, David J. M.
影响因子:
64.8
作者:
通讯作者:
--
DOI:
10.4049/jimmunol.1800118
发表时间:
2018-05-01
期刊:
Journal of immunology (Baltimore, Md. : 1950)
影响因子:
--
作者:
Burel JG;Lindestam Arlehamn CS;Khan N;Seumois G;Greenbaum JA;Taplitz R;Gilman RH;Saito M;Vijayanand P;Sette A;Peters B
通讯作者:
Peters B
影响因子:
5.4
作者:
Bua, Alessandra;Ruggeri, Melania;Molicotti, Paola
通讯作者:
Molicotti, Paola
DOI:
10.1164/rccm.201208-1352oc
发表时间:
2013-02-15
影响因子:
24.7
作者:
Adetifa, Ifedayo M.;Ota, Martin O. C.;Hill, Philip C.
通讯作者:
Hill, Philip C.