Volatiles from three genome sequenced fungi from the genus Aspergillus.

Volatiles from three genome sequenced fungi from the genus Aspergillus.
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DOI:
10.3762/bjoc.14.77
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发表时间:
2018
影响因子:
2.7
通讯作者:
Brock NL
Brock NL
中科院分区:
化学4区
文献类型:
--
作者:
Dickschat JS;Celik E;Brock NL

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采用气相色谱-质谱法对3株基因组测序的曲霉属真菌平板培养挥发物进行了分析。这三种菌株都产生萜烯,并讨论了其生物合成关系。获得的数据还与每个菌株编码的萜烯合成酶的遗传信息相关。除萜烯外,还鉴定出一系列芳香族化合物和脂肪酸和支链氨基酸代谢产生的挥发物。其中一些化合物以前没有被描述为真菌代谢物。对于哈密瓜中已知的化合物乙基(E)-庚-4-烯酸酯,提出了对Z立体异构体的结构修正。乙基(Z)-庚-4-烯酸酯也存在于曲霉中,并通过合成一个真实的标准品进行了鉴定。
The volatiles emitted by agar plate cultures of three genome sequenced fungal strains from the genus Aspergillus were analysed by GC–MS. All three strains produced terpenes for which a biosynthetic relationship is discussed. The obtained data were also correlated to genetic information about the encoded terpene synthases for each strain. Besides terpenes, a series of aromatic compounds and volatiles derived from fatty acid and branched amino acid metabolism were identified. Some of these compounds have not been described as fungal metabolites before. For the compound ethyl (E)-hept-4-enoate known from cantaloupe a structural revision to the Z stereoisomer is proposed. Ethyl (Z)-hept-4-enoate also occurs in Aspergillus clavatus and was identified by synthesis of an authentic standard.
DOI: 10.1038/nchembio.2007.29
发表时间: 2007-11-01
影响因子: 14.8
作者:
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