Strategies for containing Ebola in West Africa.

Strategies for containing Ebola in West Africa.
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DOI:
10.1126/science.1260612
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发表时间:
2014-11-21
期刊:
Science (New York, N.Y.)
影响因子:
--
通讯作者:
Galvani AP
Galvani AP
中科院分区:
其他
文献类型:
--
作者:
Pandey A;Atkins KE;Medlock J;Wenzel N;Townsend JP;Childs JE;Nyenswah TG;Ndeffo-Mbah ML;Galvani AP

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正在发生的埃博拉疫情给西非及其他地区的国家带来了令人担忧的风险。为了评估防控策略的有效性,我们建立了一个关于普通社区、医院和葬礼之间及内部埃博拉传播的随机模型,并根据利比里亚的发病数据进行了校准。我们发现,为了扭转疫情增长的趋势,必须极其紧迫地实施病例隔离、接触者追踪与隔离以及卫生葬礼措施相结合的方法。截至9月19日,在维持现状的情况下,我们的模型预测疫情将继续蔓延,预计到12月1日每日新增病例将达到224例(134例至358例),到12月15日将达到280例(184例至441例),到12月30日将达到348例(249例至545例)。
The ongoing Ebola outbreak poses an alarming risk to the countries of West Africa and beyond. To assess the effectiveness of containment strategies, we developed a stochastic model of Ebola transmission between and within the general community, hospitals, and funerals, calibrated to incidence data from Liberia. We find that a combined approach of case isolation, contact-tracing with quarantine, and sanitary funeral practices must be implemented with utmost urgency in order to reverse the growth of the outbreak. As of 19 September, under status quo, our model predicts that the epidemic will continue to spread, generating a predicted 224 (134 to 358) daily cases by 1 December, 280 (184 to 441) by 15 December, and 348 (249 to 545) by 30 December.
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