Apoptotic Cell-Derived Extracellular Vesicles: More Than Just Debris.
Apoptotic Cell-Derived Extracellular Vesicles: More Than Just Debris.
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DOI:
10.3389/fimmu.2018.01486
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发表时间:
2018
影响因子:
7.3
通讯作者:
Poon IKH
中科院分区:
文献类型:
--
作者:
Caruso S;Poon IKH
The many functions of extracellular vesicles (EVs) like exosomes and microvesicles released from healthy cells have been well characterized, particularly in relation to their roles in immune modulation. Apoptotic bodies, a major class of EV released as a product of apoptotic cell disassembly, and other types of EVs released from dying cells are also becoming recognized as key players in this emerging field. There is now increasing evidence to suggest that EVs produced during apoptosis have important immune regulatory roles, a concept relevant across different disease settings including autoimmunity, cancer, and infection. Therefore, this review focuses on how the formation of EVs during apoptosis could be a key mechanism of immune modulation by dying cells.
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影响因子:
7.2
作者:
Hochreiter-Hufford, Amelia;Ravichandran, Kodi S.
通讯作者:
Ravichandran, Kodi S.
DOI:
10.1084/jem.20050915
发表时间:
2005-12-19
期刊:
The Journal of experimental medicine
影响因子:
--
作者:
Casares N;Pequignot MO;Tesniere A;Ghiringhelli F;Roux S;Chaput N;Schmitt E;Hamai A;Hervas-Stubbs S;Obeid M;Coutant F;Métivier D;Pichard E;Aucouturier P;Pierron G;Garrido C;Zitvogel L;Kroemer G
通讯作者:
Kroemer G
影响因子:
4.4
作者:
Ferguson, TA;Herndon, J;Green, DR
通讯作者:
Green, DR
影响因子:
7.2
作者:
Distler, JHW;Huber, LC;Pisetsky, DS
通讯作者:
Pisetsky, DS
影响因子:
5.5
作者:
Farinacci, Maura;Weber, Stephan;Kaufmann, Stefan H. E.
通讯作者:
Kaufmann, Stefan H. E.