MAGNIFYING ENDOSCOPIC OBSERVATION OF THE UPPER GASTROINTESTINAL TRACT
MAGNIFYING ENDOSCOPIC OBSERVATION OF THE UPPER GASTROINTESTINAL TRACT
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放大内镜观察上胃肠道
DOI：
10.1111/j.0915-5635.2006.00610.x
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发表时间：
2006
影响因子：
5.3
通讯作者：
S. Yamazaki
中科院分区：
文献类型：
--
作者：
Y. Kumagai;M. Iida;S. Yamazaki
最新的技术进步使我们能够在内窥镜手术中获得更详细的信息。小凹模式或微血管结构的诊断允许在胃肠道肿瘤病变的早期检测。这些进步导致了适当治疗的增强选择。早期发现的癌症可以通过粘膜切除术治疗，而晚期癌症则通过手术治疗。最近，一些研究小组尝试直接获取胃肠道粘膜的活体组织学图像（虚拟组织学或光学活检）。现在，光学相干断层扫描（OCT）、共聚焦激光内窥镜和细胞内镜系统使这一概念成为可能。然而，这些技术都没有得到证实，尽管一些研究人员已经能够使用它们来增强癌症检测，并报告了这些技术的有用性。本综述评估了这些技术的优点和缺点，并描述了使用市场上可用的放大内镜设备以及新开发的细胞内镜系统对上消化道进行放大观察。通过检索MEDLINE、癌症试验登记册：国家癌症研究所（http：//cancertrials.nci.nih.gov/）和相关文章的参考文献，确定本综述的已发表和未发表数据。我们还联系了研究人员。也使用了作者自己的参考文献数据库。检索项目如下：放大内镜、细胞内镜系统、共聚焦内镜、光学相干断层扫描、接触式内镜、食管癌、Barrett食管、Barrett食管癌、胃癌、结肠癌、色素内镜、亚甲蓝等。
Recent advances in technology enable us to obtain more detailed information during endoscopic procedures. Diagnosis of the pit pattern or microvascular architecture allow the earlier detection of neoplastic lesions in the gastrointestinal tract. These advances have led to the enhanced selection of appropriate treatments. Cancers that are discovered at an early stage can be treated by mucosal resection, whereas advanced cancers are treated with surgery. Recently, some groups have tried to acquire direct in vivo histological images of gastrointestinal mucosa (virtual histology or optical biopsy). Now optical coherence tomography (OCT), confocal laser endoscopy and endo‐cytoscopy systems enable this conception. However, none of these techniques has been proven, although some investigators have been able to use them to enhance cancer detection, and have reported the usefulness of these techniques. The present review assesses the strengths and weaknesses of these technologies, and describes the magnifying observations of the upper gastrointestinal tract using magnifying endoscopy equipment available on the market as well as newly developed endo‐cytoscopy systems. Published and unpublished data for this review were identified by searches of MEDLINE, Register of Cancer Trials: National Cancer Institute (http://cancertrials.nci.nih.gov/) and references from relevant articles. We also contacted researchers. The authors’ own database of references was also used. The search items were as follows: magnifying endoscopy, endo‐cytoscopy system, confocal endoscopy, optical coherence tomography, contact endoscopy, esophageal cancer, Barrett’s esophagus, Barrett’s esophageal cancer, gastric cancer, colon cancer, chromoendoscopy, methylene blue etc.
影响因子：
56.9
作者：
Tearney, GJ;Brezinski, ME;Fujimoto, JG
通讯作者：
Fujimoto, JG