Environmental epigenetics and allergic diseases: recent advances.

Environmental epigenetics and allergic diseases: recent advances.
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DOI:
10.1111/j.1365-2222.2010.03599.x
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发表时间:
2010-11
期刊:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
影响因子:
--
通讯作者:
Miller RL
Miller RL
中科院分区:
其他
文献类型:
--
作者:
Kuriakose JS;Miller RL

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Significant strides in the understanding of the role of epigenetic regulation in asthma and allergy using both epidemiological approaches as well as experimental ones have been made. This review focuses on new research within the last two years. These include advances in determining how environmental agents implicated in airway disease can induce epigenetic changes, how epigenetic regulation can influence T helper cell (Th) differentiation and T regulatory (Treg) cell production, and new discoveries of epigenetic regulation associated with clinical outcomes.
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