Iron and infection in hemodialysis patients.
Iron and infection in hemodialysis patients.
复制标题
血液透析患者的铁和感染。
DOI:
10.1111/sdi.12168
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发表时间:
2014-01
影响因子:
1.6
通讯作者:
Johansen KL
中科院分区:
文献类型:
--
作者:
Ishida JH;Johansen KL
Intravenous iron is an important component of the treatment of anemia of end-stage renal disease (ESRD), but it is biologically plausible that iron could increase the risk of infection through impairment of neutrophil and T cell function and promotion of microbial growth. Any such increase in risk would be particularly important because infection is a significant cause of mortality and morbidity in dialysis patients. The overall evidence favors an association between iron and infection in hemodialysis patients, but the optimal iron management strategy to minimize infection risk has yet to be identified. There is a need for further research on this topic, particularly in light of increased utilization of intravenous iron following implementation of the bundled ESRD reimbursement system.
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