An emerging relationship between peripheral sympathetic nervous activity and atrial natriuretic factor.

An emerging relationship between peripheral sympathetic nervous activity and atrial natriuretic factor.
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周围交感神经活动与心房钠尿因子之间的新兴关系。

DOI:
10.1016/0024-3205(87)90119-6
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发表时间:
1987
期刊:
影响因子:
6.1
通讯作者:
J. Genest
J. Genest
中科院分区:
医学2区
文献类型:
--
作者:
O. Kuchel;W. Debinski;K. Rácz;N. Buu;R. Garcia;J. Cusson;P. Larochelle;M. Cantin;J. Genest

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The sympathetic nervous system and atrial natriuretic factor (ANF) are intimately involved in sodium, volume and blood pressure hemeostasis, particularly in response to volume and pressure overloads. Although rapid progress in this field indicates several levels of interaction between both systems, the role of sympathetic nervous activity (SNA) in ANF release remains a controversial topic. There is growing evidence that ANF is an inhibitory modulator of sympathetic outflow (which in turn, may contribute to ANF's effect) and, vice-versa, SNA attenuates the target actions of ANF. Compensatory sympathetic reactions to changes induced by ANF may also have an overriding influence on its target actions. Dopamine appears to play a special role in these interactions. It is not only a precursor of norepinephrine but probably fulfills an independent function in the regulation of salt balance, similar in many respects to that of ANF.
心房钠尿因子抑制离体灌注大鼠肠系膜动脉中交感神经刺激引起的去甲肾上腺素释放。
DOI: 10.1016/0014-2999(86)90724-7
发表时间: 1986
影响因子: 5
作者:
Nakamaru,M;Inagami,T
通讯作者: Inagami,T