Refined chromosome study helps define prognostic subgroups in most patients with primary myelodysplastic syndrome and acute myelogenous leukaemia
Refined chromosome study helps define prognostic subgroups in most patients with primary myelodysplastic syndrome and acute myelogenous leukaemia
复制标题
精细染色体研究有助于确定大多数原发性骨髓增生异常综合征和急性髓性白血病患者的预后亚组
DOI:
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发表时间:
1988
影响因子:
6.5
通讯作者:
R. Brunning
中科院分区:
文献类型:
--
作者:
J. Yunis;M. Lobell;M. Arnesen;M. Oken;M. Mayer;R. Rydell;R. Brunning
Based on a 6·1/2‐year study of 284 consecutive adult patients with primary myelodysplastic syndrome (MDS) and and acute myelogenous leukaemia (AML), we have found that refined chromosome analysis can be used as an independent prognostic indicator in the great majority of patients with MDS and AML. In MDS, the FAB subtype was also found to have prognostic value and this was enhanced when the chromosomal findings were taken into consideration. In AML, the age of the patient correlated more closely with the chromosomal changes in predicting prognosis in most patients than did the FAB classification.
DOI:
10.1056/nejm198409273111302
发表时间:
1984
期刊:
The New England journal of medicine
影响因子:
--
作者:
Yunis,JJ;Brunning,RD;Howe,RB;Lobell,M
通讯作者:
Lobell,M
影响因子:
--
作者:
通讯作者:
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影响因子:
56.9
作者:
ROWLEY, JD
通讯作者:
ROWLEY, JD