Plastid protein import and sorting: different paths to the same compartments.

Plastid protein import and sorting: different paths to the same compartments.
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DOI:
10.1016/j.pbi.2008.10.008
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发表时间:
2008-12
影响因子:
9.5
通讯作者:
Dabney-Smith, Carole
Dabney-Smith, Carole
中科院分区:
生物学2区
文献类型:
--
作者:
Cline, Kenneth;Dabney-Smith, Carole

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叶绿体含有数千种不同的蛋白质,其中95%以上由核基因编码,在细胞质中合成为前体蛋白,并输入细胞器。进口和路由的主要途径已被描述;一个一般的进口设备在叶绿体被膜和类囊体膜中的几个祖先易位酶。在这次更新中,我们集中在一些有趣的和新兴的领域:达特移位酶,它与Sec系统平行运作,但运输折叠的蛋白质;不同的路线到包膜膜,这有望了解的方式,抽搐装置排序跨膜结构域(TMDs),也可能揭示包膜和类囊体之间的发育关系;以及蛋白质进入叶绿体的新途径,包括从分泌系统的递送。
Chloroplasts contain several thousand different proteins, of which more than 95% are encoded on nuclear genes, synthesized in the cytosol as precursor proteins, and imported into the organelle. The major pathways for import and routing have been described; a general import apparatus in the chloroplast envelope and several ancestral translocases in the thylakoid membranes. In this update we focus on some interesting and emerging areas: the Tat translocase, which operates in parallel with the Sec system but transports folded proteins; different routes to the envelope membranes, which promises an understanding of the ways the Tic apparatus sorts transmembrane domains (TMDs) and may also uncover developmental relationships between envelope and thylakoids; and novel routes for proteins into chloroplasts including delivery from the secretory system.
DOI: 10.1074/jbc.m512453200
发表时间: 2006-03-03
影响因子: 4.8
作者:
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