Joint Effort towards Preventing Nutritional Deficiencies at the Extremes of Life during COVID-19.

Joint Effort towards Preventing Nutritional Deficiencies at the Extremes of Life during COVID-19.
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DOI:
10.3390/nu13051616
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发表时间:
2021-05-12
期刊:
影响因子:
5.9
通讯作者:
Agostoni C
Agostoni C
中科院分区:
医学2区
文献类型:
--
作者:
Spolidoro GCI;Azzolino D;Shamir R;Cesari M;Agostoni C

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2019冠状病毒病(COVID-19)大流行正在对全球社区和医疗保健系统构成威胁。各种形式的营养不良都可能对儿童和老年人感染SARS-CoV-2(严重急性呼吸综合征冠状病毒2)的易感性和严重程度产生负面影响。营养不良和肥胖都被认为是与感染易感性高和预后差相关的疾病。反过来,COVID-19感染可能通过高分解代谢条件恶化营养状况,使个人面临营养不良、肌肉萎缩和营养缺乏的风险。因此,营养不良与COVID-19之间的关系可能是双向的。此外,限制病毒传播所需的营养行为和身体活动的改变,正在对生活中两个极端的健康构成挑战。迄今为止,即使是最先进的卫生保健系统也未能解决这一流行病造成的令人震惊的营养不良后果。如果处理不当,我们可能会面临新一代和老一代都将经历与COVID-19相关的营养不良后果的风险。
The COVID-19 (Coronavirus disease 2019) pandemic is posing a threat to communities and healthcare systems worldwide. Malnutrition, in all its forms, may negatively impact the susceptibility and severity of SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) infection in both children and older adults. Both undernutrition and obesity have been evoked as conditions associated with a higher susceptibility to the infection and poor prognosis. In turn, the COVID-19 infection may worsen the nutritional status through highly catabolic conditions, exposing individuals to the risk of malnutrition, muscle wasting, and nutritional deficiencies. Accordingly, the relationship between malnutrition and COVID-19 is likely to be bidirectional. Furthermore, the modification of nutritional behaviors and physical activity, required to limit the spread of the virus, are posing a challenge to health at both the extremes of life. Thus far, even the most advanced healthcare systems have failed to address the alarming consequences of malnutrition posed by this pandemic. If not properly addressed, we may run the risk that new and old generations will experience the consequences of COVID-19 related malnutrition.
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