Predicting the impact of COVID-19 interruptions on transmission of gambiense human African trypanosomiasis in two health zones of the Democratic Republic of Congo
Predicting the impact of COVID-19 interruptions on transmission of gambiense human African trypanosomiasis in two health zones of the Democratic Republic of Congo
复制标题
预测 COVID-19 中断对刚果民主共和国两个卫生区冈比亚人类非洲锥虫病传播的影响
DOI:
10.1101/2020.10.26.20219485
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发表时间:
2020
期刊:
影响因子:
--
通讯作者:
Aliee M
中科院分区:
文献类型:
--
作者:
Aliee M
Many control programmes against neglected tropical diseases have been interrupted due to the coronavirus disease 2019 (COVID-19) pandemic, including those that rely on active case finding. In this study we focus ongambiensehuman African trypanosomiasis (gHAT), where active screening was suspended in the Democratic Republic of Congo (DRC) due to the pandemic. We use two independent mathematical models to predict the impact of COVID-19 interruptions on transmission and reporting and achievement of the 2030 elimination of transmission (EOT) goal for gHAT in two moderate-risk regions of the DRC. We consider different interruption scenarios, including reduced passive surveillance in fixed health facilities, and whether this suspension lasts until the end of 2020 or 2021. Our models predict an increase in the number of new infections in the interruption period only if both active screening and passive surveillance were suspended, and with a slowed reduction—but no increase—if passive surveillance remains fully functional. In all scenarios, the EOT may be slightly pushed back if no mitigation, such as increased screening coverage, is put in place. However, we emphasise that the biggest challenge will remain in the higher-prevalence regions where EOT is already predicted to be behind schedule without interruptions unless interventions are bolstered.
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影响因子:
6.4
作者:
Coffeng, Luc E.;Le Rutte, Epke A.;Medley, Graham F.
通讯作者:
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DOI:
--
发表时间:
--
期刊:
影响因子:
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Ziyin Li
影响因子:
4.3
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通讯作者:
Chitnis N
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3.8
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通讯作者:
Solano P