Porcine epidemic diarrhea virus introduction into the United States: Root cause investigation.
Porcine epidemic diarrhea virus introduction into the United States: Root cause investigation.
复制标题
DOI：
10.1016/j.prevetmed.2015.11.013
复制
发表时间：
2016-01-01
影响因子：
2.6
通讯作者：
Singrey A
中科院分区：
文献类型：
--
作者：
Scott A;McCluskey B;Brown-Reid M;Grear D;Pitcher P;Ramos G;Spencer D;Singrey A
猪流行性腹泻(PED)于2013年春季在美国被发现，来自美国养猪业多个领域的专业人士迅速做出反应，以了解和控制这种新出现的疾病。在不到两个月的时间里，这种疾病已经蔓延到13个州的200多个牛群。来自美国农业部(USDA)的专家从事实验室诊断、分析支持、流行病学专业知识和数据管理，以促进这一努力。到2014年，人们已经对这种疾病有了很多了解；然而，它是如何进入美国的问题仍然没有答案。2014年，美国农业部成立了一个调查小组，以解决这一问题，并利用非联邦调查人员难以获得的资源和伙伴关系利用现有知识。该小组与其他政府和非政府组织和个人建立了合作关系，并遵循了许多调查方法；最终得出了描述引入PED的可能机制的少量情景。为使情况可信，它必须解释：来源国的人或产品受到污染，其过境和进入美国，在广泛的地理区域内迅速传播，以及猪的暴露/感染。它必须与猪群调查和研究的结果相一致。潜在的产品必须在疫情开始之前的一段时间内合法进口，或者通过被禁止的渠道运往美国。启动了后续研究，为最可信的情景收集更多证据。在这些情况中，用来运输作为PED病毒传播混合物的散装饲料的灵活的中间散装集装箱(“饲料箱”)为累积的调查结果提供了最简单的解释。
Porcine epidemic diarrhea (PED) was identified in the United States in the spring of 2013, and professionals from many parts of the U.S. swine industry responded rapidly to understand and control the newly emerging disease. In less than two months, the disease had spread to more than 200 herds in thirteen states. Experts from the US Department of Agriculture (USDA) engaged in laboratory diagnostics, analytic support, epidemiology expertise, and data management to facilitate the effort. By 2014, a great deal had been learned about the disease; however, the question of how it entered the United States remained unanswered. In 2014, USDA formed an investigative group to address the question and leverage current knowledge with resources and partnerships not readily available to non-federal investigators. The group formed collaborations with other government and non-government organizations and individuals, and followed many avenues of inquiry; ultimately arriving at a small number of scenarios that describe possible mechanisms for PED introduction. For a scenario to be plausible, it had to explain: contamination of a person or product in the source country, its transit and entry to the United States, rapid dispersal across a wide geographic area, and exposure/infection of pigs. It had to be compatible with findings of swine herd investigations and research studies. Potential products had to have been imported legally during the time prior to the beginning of the epidemic, or delivered to the United States through prohibited channels. Follow-up studies were initiated to gather more evidence for the most plausible scenarios. Of the scenarios, flexible intermediate bulk containers (“feed totes”) used to transport bulk feed serving as fomites for movement of PED virus provided the simplest explanation for the accumulated findings of the investigation.
登录
查看更多内容
影响因子：
6.4
作者：
Huang YW;Dickerman AW;Piñeyro P;Li L;Fang L;Kiehne R;Opriessnig T;Meng XJ
通讯作者：
Meng XJ
影响因子：
11.8
作者：
Lowe J;Gauger P;Harmon K;Zhang J;Connor J;Yeske P;Loula T;Levis I;Dufresne L;Main R
通讯作者：
Main R
影响因子：
1.5
作者：
Stevenson, Gregory W.;Hoang, Hai;Yoon, Kyoungjin J.
通讯作者：
Yoon, Kyoungjin J.
影响因子：
11.8
作者：
Wang L;Byrum B;Zhang Y
通讯作者：
Zhang Y
影响因子：
9.4
作者：
Chen, Qi;Li, Ganwu;Zhang, Jianqiang
通讯作者：
Zhang, Jianqiang