Validity of myocardial infarction diagnoses in administrative databases: a systematic review.
Validity of myocardial infarction diagnoses in administrative databases: a systematic review.
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DOI：
10.1371/journal.pone.0092286
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发表时间：
2014
期刊：
影响因子：
3.7
通讯作者：
Avina-Zubieta JA
中科院分区：
文献类型：
--
作者：
McCormick N;Lacaille D;Bhole V;Avina-Zubieta JA
尽管管理数据库越来越多地用于与心肌梗死（MI）相关的研究，但这些数据库中MI诊断的有效性从未大规模综合。对报告管理数据中用于识别MI的诊断代码有效性的研究进行首次系统性综述。检索MEDLINE和EMBASE（开始至2010年11月），以查找以下研究：（a）使用管理数据识别MI;或（B）评价管理数据中MI代码的有效性;和（c）报告MI的验证统计量（敏感性、特异性、阳性预测值（PPV）、阴性预测值或Kappa评分）或足以进行计算的数据。其他文章通过手动搜索（截至2011年2月）原始论文找到。数据由两名独立的评审员提取;使用诊断准确性研究工具的质量评估对文章质量进行评估。纳入了1984-2010年发表的30项研究;大多数评估代码来自国际疾病分类（ICD）第9版。在大多数[≥50%]研究中，住院数据识别MI的灵敏度和特异性≥ 86%，大多数研究的PPV ≥ 93%。在最近的研究中，PPV较高，而当不包括心肌肌钙蛋白水平的标准（如MONICA）用作金标准时，PPV较低。MI作为死亡证明上的死亡原因也显示出较低的准确性，最大PPV为60%（对于明确的MI）。住院数据具有较高的有效性，因此可用于识别MI，但MI作为死亡证明上的死亡原因的准确性是次优的，需要对ICD-10代码的有效性进行更多的研究。当使用管理数据进行研究时，作者应认识到这些因素，如果无法获得住院数据来确认MI死亡，则应避免使用生命统计数据。
Though administrative databases are increasingly being used for research related to myocardial infarction (MI), the validity of MI diagnoses in these databases has never been synthesized on a large scale. To conduct the first systematic review of studies reporting on the validity of diagnostic codes for identifying MI in administrative data. MEDLINE and EMBASE were searched (inception to November 2010) for studies: (a) Using administrative data to identify MI; or (b) Evaluating the validity of MI codes in administrative data; and (c) Reporting validation statistics (sensitivity, specificity, positive predictive value (PPV), negative predictive value, or Kappa scores) for MI, or data sufficient for their calculation. Additonal articles were located by handsearch (up to February 2011) of original papers. Data were extracted by two independent reviewers; article quality was assessed using the Quality Assessment of Diagnostic Accuracy Studies tool. Thirty studies published from 1984–2010 were included; most assessed codes from the International Classification of Diseases (ICD)-9th revision. Sensitivity and specificity of hospitalization data for identifying MI in most [≥50%] studies was ≥86%, and PPV in most studies was ≥93%. The PPV was higher in the more-recent studies, and lower when criteria that do not incorporate cardiac troponin levels (such as the MONICA) were employed as the gold standard. MI as a cause-of-death on death certificates also demonstrated lower accuracy, with maximum PPV of 60% (for definite MI). Hospitalization data has higher validity and hence can be used to identify MI, but the accuracy of MI as a cause-of-death on death certificates is suboptimal, and more studies are needed on the validity of ICD-10 codes. When using administrative data for research purposes, authors should recognize these factors and avoid using vital statistics data if hospitalization data is not available to confirm deaths from MI.
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影响因子：
4
作者：
Bernatsky, S.;Lix, L.;Joseph, L.
通讯作者：
Joseph, L.
影响因子：
3.9
作者：
Bernatsky, Sasha;Lix, Lisa;Lacaille, Diane
通讯作者：
Lacaille, Diane
影响因子：
6.3
作者：
De Henauw, S;de Smet, P;De Backer, G
通讯作者：
De Backer, G
DOI：
10.1016/s0735-1097(00)00804-4
发表时间：
2000-09-01
影响因子：
24
作者：
Alpert, JS;Antman, E;Wood, D
通讯作者：
Wood, D
影响因子：
4.7
作者：
Barnabe, Cheryl;Joseph, Lawrence;Bernatsky, Sasha
通讯作者：
Bernatsky, Sasha