Antioxidative and Antihyaluronidase Activities of Some Constituents from the Aerial Part of Daucus carota

Antioxidative and Antihyaluronidase Activities of Some Constituents from the Aerial Part of Daucus carota
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胡萝卜地上部分某些成分的抗氧化和抗透明质酸酶活性

DOI:
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发表时间:
2001
期刊:
影响因子:
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通讯作者:
T. Nohara
T. Nohara
中科院分区:
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文献类型:
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作者:
M. Ono;C. Masuoka;Takemi Tanaka;Yasuyuki Ito;T. Nohara

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The methanol extract of the aerial part of Daucus carota var. sativus showed a stronger antioxidative activity than the standard synthetic antioxidant, 3-tert-butyl-4-hydroxyanisole (BHA). From this extract, five known compounds, luteolin 7-O-glucopyranoside (1), chrysoeriol 7-O-glucopyranoside (2), chlorogenic acid (3), maltol 3-O-glucopyranoside (4) and benzyl -glucopyranoside (5) were isolated. Among them, when 1–4 were investigated for their antioxidative activity using the ferric thiocyanate method, 1–3 indicated an antioxidative activity. The scavenging effect of 1–4 on the stable free radical, 1,1-diphenyl-2-picrylhydrazyl was also examined. Compounds 1 and 3 showed a scavenging effect. In addition, 1–3 were assayed for their inhibitory effects on the activation of inactive hyaluronidase induced by compound 48/80. All tested compounds showed this effect.
DOI: 10.1021/np980268s
发表时间: 1999-01-01
影响因子: 5.1
作者:
Wang, HB;Nair, MG;Gray, JI
通讯作者: Gray, JI