Krüppel-like transcription factors and control of pluripotency.
Krüppel-like transcription factors and control of pluripotency.
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DOI:
10.1186/1741-7007-8-125
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发表时间:
2010-09-27
期刊:
影响因子:
5.4
通讯作者:
Savatier P
中科院分区:
文献类型:
--
作者:
Bourillot PY;Savatier P
Recent papers have demonstrated a role for Krüppel-like transcription factors 2, 4 and 5 in the control of mouse embryonic stem cell pluripotency. However, it is not clear whether each factor has a unique role or whether they are functionally redundant. A paper by Parisi and colleagues in BMC Biology now sheds light on the mechanism by which Klf5 regulates pluripotency. See research article http://www.biomedcentral.com/1741-7007/8/128
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