Decrease in serum IgE associated with limited restriction in energy intake to treat toddler's diarrhea
Decrease in serum IgE associated with limited restriction in energy intake to treat toddler's diarrhea
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血清 IgE 降低与限制能量摄入以治疗幼儿腹泻相关
DOI：
10.1016/0031-9384(91)90248-m
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发表时间：
1991
影响因子：
2.9
通讯作者：
G. Grifi
中科院分区：
文献类型：
--
作者：
M. Ciampolini;P. Becherucci;A. Giommi;D. Vicarelli;S. Seminara;S. Bini;G. Grifi
幼儿腹泻可能是一种过敏性疾病，可以通过在喂养中教育“内在自发性”来避免其复发，即，通过教育，在进餐开始时，减少进食的刺激，这是有限的和可重复的。因此，在16名实验儿童与16名对照儿童（年龄均为1至4岁）进行随机比较，在7个月的饮食治疗前后对血清IgE进行了研究。在饮食治疗前后，通过7天的书面日记测量依从性，同时通过PRIST测量血清IgE。在接受治疗的儿童中，能量摄入减少了21%（p<0.05），水果和非淀粉蔬菜摄入量增加了约5倍。“内在自发性”组血清IgE水平下降13.9± 43.5U/ml，对照组升高33.2± 50.5U/ml（P<0.01）。在所有儿童中，检查之间的差异与NSV接受度的增加显著相关（r= 0.51，p<0.005）。NSV对2项肌肉面积、2项症状、2%生长、15项营养指标、5项免疫指标和3项肝脏指标的总体影响经MANOVA分析均达到显著水平（p<0.01）。“内在自发性”教育可能是预防2 ~ 3岁儿童暴饮暴食、腹泻复发和IgE升高的有效工具。
Toddler's diarrhea may be an allergic disease and its recurrences can be avoided with education to “internal spontaneity” in feeding, i.e., by education to a limited and reproducible decrease in eating incentives at the onset of meals. Serum IgE was thus investigated in 16 experimental children in a random comparison with 16 controls, all aged 1 to 4 years, before and after seven months' dietary treatment. Compliance was measured with a seven-day written diary, while serum IgE was measured by PRIST, before and after dietary treatment. A 21 % decrease in energy intake (p<0.05) and about five times increase in fruit and nonstarchy vegetable intake amount was seen in treated children. A decrease in serum IgE level of 13.9±43.5 U/ml was found in the “internal spontaneity” group, as opposed to an increase of 33.2±50.5 U/ml in the control one (p<0.01). The differences between examinations were significantly correlated to the increase in NSV acceptance in all children plotted together (r=.51, p<0.005). The overall NSV effect on the changes of the 2 muscle areas, 2 symptoms, and 2 percent growth, 15 nutritional, 5 immune and 3 hepatic indices was significant with MANOVA (p<0.01). The education to “internal spontaneity” may be a useful tool for prevention of overeating, diarrhea recurrences and IgE increase in the second/third year of life.
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