Diffusion of Knots along DNA Confined in Nanochannels
Diffusion of Knots along DNA Confined in Nanochannels
复制标题
结沿着限制在纳米通道中的 DNA 扩散
DOI:
10.1021/acs.macromol.0c00561
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发表时间:
2020
期刊:
影响因子:
5.5
通讯作者:
Dorfman, Kevin D.
中科院分区:
文献类型:
--
作者:
Ma, Zixue;Dorfman, Kevin D.
We study the diffusion of knots along relaxed deoxyribonucleic acid (DNA) in nanochannels using a nanofluidic “knot factory” device for knot generation. The apparent scaling exponent for the growth in the ensemble-averaged mean-squared displacement is 0.82 ± 0.01 when accounting for random errors and [0.79, 0.88] when accounting for systematic errors. Both estimates indicate subdiffusion and support a model of self-reptation. These results contradict the prevailing theory for knot diffusion along nanochannel-confined DNA, where knot region breathing is presumed to control knot diffusion in long polymers, but are consistent with previous observations of self-reptation of knots for unconfined DNA under tension.
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影响因子:
5.5
作者:
Muralidhar, Abhiram;Dorfman, Kevin D.
通讯作者:
Dorfman, Kevin D.
影响因子:
10.8
作者:
Levy SL;Mannion JT;Cheng J;Reccius CH;Craighead HG
通讯作者:
Craighead HG
DOI:
10.1529/biophysj.105.074682
发表时间:
2006
期刊:
Biophysical journal.
影响因子:
--
作者:
Vologodskii,Alexander
通讯作者:
Vologodskii,Alexander
影响因子:
14.9
作者:
Günther K;Mertig M;Seidel R
通讯作者:
Seidel R
DOI:
10.1209/epl/i2006-10312-5
发表时间:
2006-11-01
期刊:
EUROPHYSICS LETTERS
影响因子:
--
作者:
Metzler, R.;Reisner, W.;Sokolov, I. M.
通讯作者:
Sokolov, I. M.