'Long-COVID': a cross-sectional study of persisting symptoms, biomarker and imaging abnormalities following hospitalisation for COVID-19.
'Long-COVID': a cross-sectional study of persisting symptoms, biomarker and imaging abnormalities following hospitalisation for COVID-19.
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DOI：
10.1136/thoraxjnl-2020-215818
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发表时间：
2021-04
期刊：
影响因子：
10
通讯作者：
ARC Study Group
中科院分区：
文献类型：
--
作者：
Mandal S;Barnett J;Brill SE;Brown JS;Denneny EK;Hare SS;Heightman M;Hillman TE;Jacob J;Jarvis HC;Lipman MCI;Naidu SB;Nair A;Porter JC;Tomlinson GS;Hurst JR;ARC Study Group
COVID-19之后，大量患者在没有评估康复情况的情况下出院。在384例患者（平均年龄59.9岁; 62%为男性）中，出院后中位随访时间为54天，53%报告持续呼吸困难，34%报告咳嗽，69%报告疲乏。14.6%有抑郁症。在生物标志物升高的患者中，分别有30.1%和9.5%的患者持续升高d-二聚体和CRP。38%的胸片仍异常，9%恶化。COVID-19住院后的系统随访确定了身体和心理症状负担的轨迹，血液生物标志物的恢复和成像，可用于告知康复和/或进一步调查的需要。
Large numbers of people are being discharged from hospital following COVID-19 without assessment of recovery. In 384 patients (mean age 59.9 years; 62% male) followed a median 54 days post-discharge, 53% reported persistent breathlessness, 34% cough and 69% fatigue. 14.6% had depression. In those discharged with elevated biomarkers, 30.1% and 9.5% had persistently elevated d-dimer and CRP respectively. 38% of chest radiographs remained abnormal with 9% deteriorating. Systematic follow-up after hospitalisation with COVID-19 identifies the trajectory of physical and psychological symptom burden, recovery of blood biomarkers and imaging which could be used to inform the need for rehabilitation and/or further investigation.
影响因子：
10
作者：
Hui, DS;Joynt, GM;Sung, JJY
通讯作者：
Sung, JJY
影响因子：
12.7
作者：
Halpin, Stephen J.;McIvor, Claire;Sivan, Manoj
通讯作者：
Sivan, Manoj
影响因子：
3
作者：
Wei, Jiangping;Yang, Hong;Wan, Chengfeng
通讯作者：
Wan, Chengfeng