The hyperspectral imaging endoscope: a new tool for in vivo cancer detection
The hyperspectral imaging endoscope: a new tool for in vivo cancer detection
复制标题
高光谱成像内窥镜：体内癌症检测的新工具
DOI：
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发表时间：
2004
期刊：
影响因子：
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通讯作者：
D. Farkas
中科院分区：
文献类型：
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作者：
E. Lindsley;E. Wachman;D. Farkas
我们开发了一种新的内窥镜，允许非接触，快速（亚秒级）采集体内组织的偏振光谱图像。其目的是探索各种光学对比机制（如光吸收，反射，散射和荧光），以寻找临床环境中早期癌症检测的新方法。我们的第一个新的癌症检测实现是基于一个身体的光谱工作，采用弹性散射（米氏）理论来估计在给定介质中的散装散射体的大小-在我们的情况下，肺的上皮组织。本文介绍了高光谱成像内窥镜的新设计，以及我们将其用于肺上皮细胞异型增生和癌症早期检测的初步经验。
We developed a new endoscope that allows for non-contact, rapid (sub-second) acquisition of polarized spectral images of tissue in vivo. The intent was to enable exploration of a variety of optical contrast mechanisms (such as light absorption, reflectance, scattering, and fluorescence) in a search for new methods of early cancer detection in a clinical setting. Our first new implementation for cancer detection is based on a body of spectroscopic work that employs elastic scattering (Mie) theory to estimate the size of bulk scatterers in a given medium - in our case, the epithelial tissue of lungs. This paper describes the novel design of the Hyperspectral Imaging Endoscope, and our initial experiences with employing it for the early detection of dysplasia and cancer in lung epithelia.
影响因子：
29.4
作者：
Georgakoudi, I;Jacobson, BC;Feld, MS
通讯作者：
Feld, MS