An attenuation field network for dedicated cone beam breast CT with short scan and offset detector geometry.
An attenuation field network for dedicated cone beam breast CT with short scan and offset detector geometry.
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DOI：
10.1038/s41598-023-51077-1
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发表时间：
2024-01-03
影响因子：
4.6
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中科院分区：
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--
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全扫描，偏移检测器几何锥束CT的可行性已经证明了几个临床应用。对于具有偏移检测器几何的全扫描采集，可以在图像重建期间利用互补视图的数据冗余。设想一个直立乳房CT系统，我们建议获取短扫描数据与偏移检测器几何。为了解决由此产生的不完整数据，我们开发了一个自监督衰减场网络（AFN）。AFN通过基于坐标的表示和已知的成像物理来利用锥束CT数据的固有冗余。经过训练的AFN可以使用各自的坐标查询衰减系数或合成包括缺失投影在内的投影数据。使用临床锥形束乳腺CT数据集（n = 50）评估AFN。传统的分析和迭代重建方法无法重建不完整的数据，而AFN重建与使用全扫描、全检测器数据获得的参考重建在图像噪声、图像对比度和钙化半最大值全宽度方面没有统计学差异。本研究表明，同时短扫描和偏移检测器几何用于专用乳腺CT成像的可行性。提出的AFN技术有可能扩展到其他锥形束CT应用。
The feasibility of full-scan, offset-detector geometry cone-beam CT has been demonstrated for several clinical applications. For full-scan acquisition with offset-detector geometry, data redundancy from complementary views can be exploited during image reconstruction. Envisioning an upright breast CT system, we propose to acquire short-scan data in conjunction with offset-detector geometry. To tackle the resulting incomplete data, we have developed a self-supervised attenuation field network (AFN). AFN leverages the inherent redundancy of cone-beam CT data through coordinate-based representation and known imaging physics. A trained AFN can query attenuation coefficients using their respective coordinates or synthesize projection data including the missing projections. The AFN was evaluated using clinical cone-beam breast CT datasets (n = 50). While conventional analytical and iterative reconstruction methods failed to reconstruct the incomplete data, AFN reconstruction was not statistically different from the reference reconstruction obtained using full-scan, full-detector data in terms of image noise, image contrast, and the full width at half maximum of calcifications. This study indicates the feasibility of a simultaneous short-scan and offset-detector geometry for dedicated breast CT imaging. The proposed AFN technique can potentially be expanded to other cone-beam CT applications.
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