18F-FDG PET/CT imaging in oncology.

18F-FDG PET/CT imaging in oncology.
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DOI:
10.4103/0256-4947.75771
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发表时间:
2011-01
影响因子:
1.6
通讯作者:
Bomanji J
Bomanji J
中科院分区:
医学4区
文献类型:
--
作者:
Almuhaideb A;Papathanasiou N;Bomanji J

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准确的诊断和分期对于癌症患者的最佳管理至关重要。结合计算机断层扫描(18 F-FDG PET/CT)的2-脱氧-2-[氟-18]氟-D-葡萄糖正电子发射断层扫描已成为检测各种癌症的强大成像工具。PET和CT的联合采集与单独的PET或CT相比具有协同优势,并最大限度地减少了各自的局限性。它是一个有价值的工具,分期和重新分期的一些肿瘤,并在检测复发的无症状患者与肿瘤标志物水平上升和患者的传统成像技术的阴性或可疑的结果具有重要作用。它还允许监测对治疗的反应,并允许及时修改治疗方案。在大约27%的患者中,改变了管理过程。本综述为肿瘤学家/放射治疗师以及临床和外科专家在肿瘤学中使用18F-FDG PET/CT提供了指导。
Accurate diagnosis and staging are essential for the optimal management of cancer patients. Positron emission tomography with 2-deoxy-2-[fluorine-18]fluoro- D-glucose integrated with computed tomography (18F-FDG PET/CT) has emerged as a powerful imaging tool for the detection of various cancers. The combined acquisition of PET and CT has synergistic advantages over PET or CT alone and minimizes their individual limitations. It is a valuable tool for staging and restaging of some tumors and has an important role in the detection of recurrence in asymptomatic patients with rising tumor marker levels and patients with negative or equivocal findings on conventional imaging techniques. It also allows for monitoring response to therapy and permitting timely modification of therapeutic regimens. In about 27% of the patients, the course of managment is changed. This review provides guidance for oncologists/ radiotherapists and clinical and surgical specialists on the use of 18F-FDG PET/CT in oncology.
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