Treating Acne in Transgender Persons Receiving Testosterone: A Practical Guide.
Treating Acne in Transgender Persons Receiving Testosterone: A Practical Guide.
复制标题
DOI：
10.1007/s40257-021-00665-w
复制
发表时间：
2022-03
影响因子：
7.3
通讯作者：
Yeung H
中科院分区：
文献类型：
--
作者：
Radi R;Gold S;Acosta JP;Barron J;Yeung H
接受男性化激素治疗的变性人在开始和维持睾酮治疗时，会经历一系列广泛的皮肤效应。痤疮是许多接受睾酮治疗的跨性别患者最常见的不良反应之一。痤疮会恶化身体形象和心理健康，对跨性别患者的生活质量有显著影响。在为跨性别患者提供护理时，需要进行临床和文化上的培训和认识。这篇文章提供了一个实用的指南，睾酮诱导痤疮在跨男性患者的治疗。建议创建一个温馨的临床环境，采取性别包容的历史，并进行以患者为中心的身体检查有关痤疮护理。评估生殖潜力和适当的避孕方法之前，处方痤疮治疗致畸潜力的跨男性患者进行检查。痤疮治疗与性别肯定疗法之间的相互作用进行了探讨。对于严重或难治性痤疮患者，应检查异维甲酸处方的适应症、禁忌症和障碍，如美国iPLEDGE计划。痤疮护理采用多学科方法，包括心理健康、生殖健康、性别确认激素治疗和手术，以指导异维甲酸治疗。
Transgender persons who undergo masculinizing hormone therapy experience a wide array of dermatologic effects as they initiate and maintain testosterone therapy. Acne is one of the most common adverse effects for many transmasculine patients receiving testosterone. Acne can worsen body image and mental health, with significant impact on quality of life in transgender patients. Specific training and awareness are needed for a clinically and culturally competent encounter while providing care for the transgender patient. This article provides a practical guide for the treatment of testosterone-induced acne in transmasculine patients. Recommendations on creating a welcoming clinical setting, taking a gender-inclusive history, and conducting a patient-centered physical examination relevant to acne care are provided. Assessment of reproductive potential and the appropriate contraceptive methods before prescribing acne treatment with teratogenic potential in transmasculine patients are examined. Interactions between acne treatments with gender-affirming therapies are explored. For patients with severe or treatment-refractory acne, indications, contraindications, and barriers to isotretinoin prescription, such as the US iPLEDGE program, are examined. Multidisciplinary approaches to acne care, involving mental health, reproductive health, gender-affirming hormone therapy and surgeries, are adopted to guide isotretinoin treatment.
登录
查看更多内容
DOI：
10.1016/j.chc.2019.02.016
发表时间：
2019-07-01
影响因子：
2.4
作者：
Johnson, Brandon;Leibowitz, Scott;Herbert, Sarah E.
通讯作者：
Herbert, Sarah E.
DOI：
10.3390/molecules21081063
发表时间：
2016-08-13
期刊：
Molecules (Basel, Switzerland)
影响因子：
--
作者：
Fox L;Csongradi C;Aucamp M;du Plessis J;Gerber M
通讯作者：
Gerber M
影响因子：
2
作者：
Carswell, Jeremi M;Roberts, Stephanie A
通讯作者：
Roberts, Stephanie A
影响因子：
1.5
作者：
Covelli, Isabela;Ahrens, Kym;Boos, Markus D.
通讯作者：
Boos, Markus D.
影响因子：
5.8
作者：
Giltay, EJ;Gooren, LJG
通讯作者：
Gooren, LJG