Functional boundaries in the human cerebellum revealed by a multi-domain task battery.
Functional boundaries in the human cerebellum revealed by a multi-domain task battery.
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DOI:
10.1038/s41593-019-0436-x
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发表时间:
2019-08
影响因子:
25
通讯作者:
Diedrichsen J
中科院分区:
文献类型:
--
作者:
King M;Hernandez-Castillo CR;Poldrack RA;Ivry RB;Diedrichsen J
There is compelling evidence that the human cerebellum is engaged in a wide array of motor and cognitive tasks. A fundamental question centers on whether the cerebellum is organized into distinct functional subregions. To address this question, we employed a rich task battery designed to tap into a broad range of cognitive processes. During four functional MRI sessions, participants performed a battery of 26 diverse tasks comprising 47 unique conditions. Using the data from this multi-domain task battery, we derived a comprehensive functional parcellation of the cerebellar cortex and evaluated it by predicting functional boundaries in a novel set of tasks. The new parcellation successfully identified distinct functional subregions, providing significant improvements over existing parcellations derived from task-free data. Lobular boundaries, commonly used to summarize functional data, did not coincide with functional subdivisions. The new parcellation provides a functional atlas to guide future neuroimaging studies.
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影响因子:
3.5
作者:
Poldrack RA;Kittur A;Kalar D;Miller E;Seppa C;Gil Y;Parker DS;Sabb FW;Bilder RM
通讯作者:
Bilder RM
影响因子:
4.3
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Dosenbach, Nico U. F.