COVID-19 vaccine acceptance among pregnant, breastfeeding, and nonpregnant reproductive-aged women.
COVID-19 vaccine acceptance among pregnant, breastfeeding, and nonpregnant reproductive-aged women.
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DOI：
10.1016/j.ajogmf.2021.100403
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发表时间：
2021-09
影响因子：
6.3
通讯作者：
Gyamfi-Bannerman C
中科院分区：
文献类型：
--
作者：
Sutton D;D'Alton M;Zhang Y;Kahe K;Cepin A;Goffman D;Staniczenko A;Yates H;Burgansky A;Coletta J;Williams Z;Gyamfi-Bannerman C
尽管针对COVID-19的大规模疫苗接种可能被证明是结束这一致命大流行病的最有效方法，但公众对疫苗接种仍然存在担忧和犹豫不决。由于孕妇和育龄妇女占人口的很大比例，特别关注COVID-19疫苗接种，因此这项调查旨在调查他们在我们自己的机构内的当前态度和信念。本研究旨在了解孕妇、非孕妇和母乳喂养受访者对疫苗的接受程度，并阐明与COVID-19疫苗接受程度相关的因素。我们对我们机构的所有女性（包括患者、提供者和工作人员）进行了一项匿名在线调查，评估COVID-19疫苗接种的接受率。受访者通过以下三种方式之一联系：电子邮件、广告传单以及在虚拟市政霍尔斯分发关于COVID-19疫苗的快速响应代码。根据他们的回答，受访者被分为3个相互排斥的组：（1）未怀孕的受访者，（2）怀孕的受访者，和（3）母乳喂养的受访者。主要结果是接受疫苗接种。计算患病率以确定多个患者水平因素对疫苗可接受性的独立影响。该调查于2021年1月7日至2021年1月29日进行，共有1012名受访者，其中466名（46.9%）为非西班牙裔白色，108名（10.9%）为非西班牙裔黑人，286名（28.8%）为西班牙裔，82名（8.2%）为非西班牙裔亚洲人。中位年龄为36岁（四分位距，25-47岁）。在所有受访者中，656名受访者（64.8%）未怀孕，216名（21.3%）怀孕，122名（12.1%）母乳喂养。作为复合变量进行评价时，慢性合并症无差异（表1）。共有390名受访者（39.2%）报告在医疗保健领域工作。未怀孕的受访者最有可能接受疫苗接种（457名受访者，76.2%; P<.001），母乳喂养的受访者第二大可能性（55.2%）。怀孕的受访者接受疫苗的比例最低（44.3%; P<.001）。患病率比率显示，除非西班牙裔亚裔受访者外，所有非白人种族均接受了疫苗接种，而讲西班牙语的受访者接受疫苗接种的可能性较低（表3）。在我们的队列中，未发现在医疗保健部门工作与疫苗接受相关。在这项仅对单一机构的女性进行的调查研究中，非白人或非亚洲种族的怀孕受访者比非怀孕和母乳喂养的受访者更有可能拒绝接种疫苗。从事医疗保健工作与疫苗接受度无关。
Although mass vaccination against COVID-19 may prove to be the most efficacious end to this deadly pandemic, there remain concern and indecision among the public toward vaccination. Because pregnant and reproductive-aged women account for a large proportion of the population with particular concerns regarding vaccination against COVID-19, this survey aimed at investigating their current attitudes and beliefs within our own institution. This study aimed to understand vaccine acceptability among pregnant, nonpregnant, and breastfeeding respondents and elucidate factors associated with COVID-19 vaccine acceptance. We administered an anonymous online survey to all women (including patients, providers, and staff) at our institution assessing rates of acceptance of COVID-19 vaccination. Respondents were contacted in 1 of 3 ways: by email, advertisement flyers, and distribution of quick response codes at virtual town halls regarding the COVID-19 vaccine. Based on their responses, respondents were divided into 3 mutually exclusive groups: (1) nonpregnant respondents, (2) pregnant respondents, and (3) breastfeeding respondents. The primary outcome was acceptance of vaccination. Prevalence ratios were calculated to ascertain the independent effects of multiple patient-level factors on vaccine acceptability. The survey was administered from January 7, 2021, to January 29, 2021, with 1012 respondents of whom 466 (46.9%) identified as non-Hispanic White, 108 (10.9%) as non-Hispanic Black, 286 (28.8%) as Hispanic, and 82 (8.2%) as non-Hispanic Asian. The median age was 36 years (interquartile range, 25–47 years). Of all the respondents, 656 respondents (64.8%) were nonpregnant, 216 (21.3%) were pregnant, and 122 (12.1%) were breastfeeding. There was no difference in chronic comorbidities when evaluated as a composite variable (Table 1). A total of 390 respondents (39.2%) reported working in healthcare. Nonpregnant respondents were most likely to accept vaccination (457 respondents, 76.2%; P<.001) with breastfeeding respondents the second most likely (55.2%). Pregnant respondents had the lowest rate of vaccine acceptance (44.3%; P<.001). Prevalence ratios revealed all non-White races except for non-Hispanic Asian respondents, and Spanish-speaking respondents were less likely to accept vaccination (Table 3). Working in healthcare was not found to be associated with vaccine acceptance among our cohort. In this survey study of only women at a single institution, pregnant respondents of non-White or non-Asian races were more likely to decline vaccination than nonpregnant and breastfeeding respondents. Working in healthcare was not associated with vaccine acceptance.
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DOI：
10.15585/mmwr.mm6944e3
发表时间：
2020-11-06
期刊：
MMWR. Morbidity and mortality weekly report
影响因子：
--
作者：
Zambrano LD;Ellington S;Strid P;Galang RR;Oduyebo T;Tong VT;Woodworth KR;Nahabedian JF 3rd;Azziz-Baumgartner E;Gilboa SM;Meaney-Delman D;CDC COVID-19 Response Pregnancy and Infant Linked Outcomes Team
通讯作者：
CDC COVID-19 Response Pregnancy and Infant Linked Outcomes Team
DOI：
10.1016/s2468-2667(21)00012-8
发表时间：
2021-04
期刊：
The Lancet. Public health
影响因子：
--
作者：
Schwarzinger M;Watson V;Arwidson P;Alla F;Luchini S
通讯作者：
Luchini S
BNT162B2 mRNA COVID-19疫苗的安全性和功效。
DOI：
10.1056/nejmoa2034577
发表时间：
2020-12-31
期刊：
The New England journal of medicine
影响因子：
--
作者：
Polack FP;Thomas SJ;Kitchin N;Absalon J;Gurtman A;Lockhart S;Perez JL;Pérez Marc G;Moreira ED;Zerbini C;Bailey R;Swanson KA;Roychoudhury S;Koury K;Li P;Kalina WV;Cooper D;Frenck RW Jr;Hammitt LL;Türeci Ö;Nell H;Schaefer A;Ünal S;Tresnan DB;Mather S;Dormitzer PR;Şahin U;Jansen KU;Gruber WC;C4591001 Clinical Trial Group
通讯作者：
C4591001 Clinical Trial Group
影响因子：
13.8
作者：
Muñoz-Price LS;Nattinger AB;Rivera F;Hanson R;Gmehlin CG;Perez A;Singh S;Buchan BW;Ledeboer NA;Pezzin LE
通讯作者：
Pezzin LE
DOI：
10.1016/j.jhin.2020.11.020
发表时间：
2021-03
期刊：
The Journal of hospital infection
影响因子：
--
作者：
Gagneux-Brunon A;Detoc M;Bruel S;Tardy B;Rozaire O;Frappe P;Botelho-Nevers E
通讯作者：
Botelho-Nevers E