Transverse false tendons in the left ventricular cavity are associated with early repolarization.

Transverse false tendons in the left ventricular cavity are associated with early repolarization.
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左心室腔内的横向假腱与早期复极相关

DOI:
10.1371/journal.pone.0125173
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发表时间:
2015
期刊:
影响因子:
3.7
通讯作者:
Wu C
Wu C
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Liu Y;Mi N;Zhou Y;An P;Bai Y;Guo Y;Hong C;Ji Z;Ye P;Wu C

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背景左室假肌腱与心前区杂音、室性心律失常及部分复极异常有关。早期复极是复极异常的一种特殊类型。目的探讨左心室肥厚与内质网的关系。方法对99例健康受试者和33例ER患者进行回顾性研究。早期复极定义为至少2个下壁或侧壁导联的QRS-ST交界处较基线升高0.1 mV,表现为QRS模糊或切迹。每个参与者都接受了超声心动图二次谐波成像检查,并记录了LVFT的附着物。结果99例健康受试者中,82例(83%)出现93个左心功能不全。在93例左心室中,大多数(79/93,84.9%)为纵向型,起源于基底室间隔(IVS),向左心室游离壁心尖方向发展。内异症组和对照组之间左心室的位置有显著差异(P<0.0001)。内异症组与对照组相比,室间隔中部至游离壁中部的LVFT更为常见(47.5%vs.6.5%,P<0.0001)。内异症组中,仅有21%的左心室游离壁基底段至心尖段存在左心功能不全,而对照组为84.9%(P<0.0001)。ER组的LVFT趋势分布与对照组相比也有显著差异(P<0.05)。结论超声心动图可直观显示左心室肥厚。从室间隔底部至左室游离壁心尖段的LVFT可能是左室腔内的正常解剖结构。相反,左室腔内横断的假肌腱可能与ER有关。
Background Left ventricular false tendons (LVFTs) are related to precordial murmurs, ventricular arrhythmias and some repolarization abnormalities. Early repolarization (ER) is a specific type of repolarization abnormality. Objective The aim of the present study was to investigate the relationship between LVFTs and ER. Methods This study retrospectively included 99 consecutive healthy subjects and 33 patients with ER. Early repolarization was defined as an elevation of the QRS-ST junction of >0.1 mV from baseline in at least 2 inferior or lateral leads, manifested as QRS slurring or notching. Each participant was examined using echocardiography with second harmonic imaging, and the attachments of the LVFTs were recorded. Results A total of 93 LVFTs were present in 82 (83%) of the 99 healthy subjects. Of these 93 LVFTs, the majority (79/93, or 84.9%) were longitudinal-type LVFTs, which originated from the basal interventricular septum (IVS) and progressed toward the apical segment of the left ventricular free wall. There were significant differences in the positioning of the LVFTs between the ER patients and control (P < 0.0001). LVFTs between mid-IVS to the middle of the LV free wall were found more common in patients with ER compared with control subjects (47.5% vs. 6.5%, P < 0.0001). In the ER group, LVFTs between the basal IVS to the apical segment of LV free wall were only identified in 21% of the LVFTs, compared to a value of 84.9% for the control group (P < 0.0001). The distribution of LVFT trends in the ER group was also significantly different from that in the control group (P < 0.05). Conclusions LVFTs are commonly visualized using echocardiography. An LVFT from the basal IVS to the apical segment of the left ventricular free wall may be a normal anatomical structure in the left ventricular cavity. On the contrary, transverse false tendons in the left ventricular cavity may be associated with ER.
DOI: 10.1098/rsta.2008.0230
发表时间: 2009-01-28
影响因子: 5
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DOI: 10.1016/j.hrthm.2012.06.036
发表时间: 2012-10
期刊: HEART RHYTHM
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