Prevalence and risks of tuberculosis multimorbidity in low-income and middle-income countries: a meta-review.

Prevalence and risks of tuberculosis multimorbidity in low-income and middle-income countries: a meta-review.
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低收入和中等收入国家的结核病多种病的患病率和风险:元评估。

DOI:
10.1136/bmjopen-2022-060906
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发表时间:
2022-09-29
期刊:
影响因子:
2.9
通讯作者:
Siddiqi, Najma
Siddiqi, Najma
中科院分区:
医学3区
文献类型:
--
作者:
Jarde, Alexander;Romano, Eugenia;Afaq, Saima;Elsony, Asma;Lin, Yan;Huque, Rumana;Elsey, Helen;Siddiqi, Kamran;Stubbs, B.;Siddiqi, Najma

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结核病与其他慢性疾病(结核病多病)的共存增加了管理的复杂性,并对健康结果产生不利影响。我们的目的是通过系统地回顾以前发表的系统综述,绘制出结核病患者中一种或多种慢性疾病的患病率和相关的健康风险。系统评价的系统评价(meta-review)。低收入和中等收入国家。我们检索了Medline、Embase、PsycINFO、社会科学引文索引、科学引文索引、新兴资源引文索引和会议文集引文索引以及世卫组织全球索引Medicus,从成立到2020年10月23日,联系了作者并审查了参考文献列表。对独立审稿人筛选标题、摘要和全文,提取数据并评估纳入的评论的质量(AMSTAR2)。我们纳入了中低收入结核病多病人群的系统评价报告数据,并对其进行了叙述性综合。我们排除了针对儿童或特定亚群体(例如,被监禁的人)的评论。结核病多病的患病率或风险(原发性);疾病负担(继发性)的任何衡量标准。从7557个搜索结果中,包括54个,代表6296000名结核病患者。我们发现,结核病患者中最常见的疾病是抑郁症(45.19%,95% CI: 38.04%至52.55%,25项研究,4903名参与者,I2=96.28%,高质量),HIV (31.81%, 95% CI: 27.83%至36.07%,68项研究,62 696名参与者,I2=98%,高质量)和糖尿病(17.7%,95% CI: 15.1%至20.0.5%,48项研究,48,036名参与者,I2=98.3%,极低质量)。我们确定了在很大一部分结核病患者中同时发生的几种慢性疾病。尽管受到文献质量和差距的限制,这一关于结核病多发病的首次荟萃综述强调了慢性疾病对结核病患者造成的额外健康负担的严重程度。CRD42020209012。
Co-occurrence of tuberculosis (TB) with other chronic conditions (TB multimorbidity) increases complexity of management and adversely affects health outcomes. We aimed to map the prevalence of the co-occurrence of one or more chronic conditions in people with TB and associated health risks by systematically reviewing previously published systematic reviews. Systematic review of systematic reviews (meta-review). Low-income and middle-income countries (LMICs). We searched in Medline, Embase, PsycINFO, Social Sciences Citation Index, Science Citation Index, Emerging Sources Citation Index and Conference Proceedings Citation Index, and the WHO Global Index Medicus from inception to 23 October 2020, contacted authors and reviewed reference lists. Pairs of independent reviewers screened titles, abstracts and full texts, extracted data and assessed the included reviews’ quality (AMSTAR2). We included systematic reviews reporting data for people in LMICs with TB multimorbidity and synthesised them narratively. We excluded reviews focused on children or specific subgroups (eg, incarcerated people). Prevalence or risk of TB multimorbidity (primary); any measure of burden of disease (secondary). From the 7557 search results, 54 were included, representing >6 296 000 people with TB. We found that the most prevalent conditions in people with TB were depression (45.19%, 95% CI: 38.04% to 52.55%, 25 studies, 4903 participants, I2=96.28%, high quality), HIV (31.81%, 95% CI: 27.83% to 36.07%, 68 studies, 62 696 participants, I2=98%, high quality) and diabetes mellitus (17.7%, 95% CI: 15.1% to 20.0.5%, 48 studies, 48,036 participants, I2=98.3%, critically low quality). We identified several chronic conditions that co-occur in a significant proportion of people with TB. Although limited by varying quality and gaps in the literature, this first meta-review of TB multimorbidity highlights the magnitude of additional ill health burden due to chronic conditions on people with TB. CRD42020209012.
DOI: 10.1016/s0140-6736(18)32203-7
发表时间: 2018-11-10
期刊: Lancet (London, England)
影响因子: --
作者:
GBD 2017 Causes of Death Collaborators
通讯作者: GBD 2017 Causes of Death Collaborators
DOI: 10.1093/gerona/glaa017
发表时间: 2020-08-01
影响因子: 5.1
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