Bursts generate a non-reducible spike-pattern code.

Bursts generate a non-reducible spike-pattern code.
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DOI:
10.3389/neuro.01.002.2009
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发表时间:
2009-05
影响因子:
4.3
通讯作者:
Samengo I
Samengo I
中科院分区:
医学2区
文献类型:
--
作者:
Eyherabide HG;Rokem A;Herz AV;Samengo I

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在单神经元水平上,精确定时的尖峰可以构成放电率代码或利用连续尖峰之间的相对时序的尖峰模式代码。这种时间模式对信息传输有重大贡献的假设几乎没有实验支持。通过使用蚱蜢听觉受体作为模型系统,我们表明尖峰之间的相关性可用于表示行为相关的刺激。这些相关性反映了尖峰序列的内部结构:一系列突发状模式。我们证明,具有不同尖峰计数的突发编码不同的刺激特征,因此大约 20% 的传输信息对应于区分不同的特征,其余 80% 用于及时分配这些特征。在这个尖峰模式代码中,刺激的内容和时间分别编码在每个突发的持续时间和突发开始的时间中。鉴于爆发放电的普遍存在,我们预计其他神经系统也会有类似的发现。
At the single-neuron level, precisely timed spikes can either constitute firing-rate codes or spike-pattern codes that utilize the relative timing between consecutive spikes. There has been little experimental support for the hypothesis that such temporal patterns contribute substantially to information transmission. By using grasshopper auditory receptors as a model system, we show that correlations between spikes can be used to represent behaviorally relevant stimuli. The correlations reflect the inner structure of the spike train: a succession of burst-like patterns. We demonstrate that bursts with different spike counts encode different stimulus features, such that about 20% of the transmitted information corresponds to discriminating between different features, and the remaining 80% is used to allocate these features in time. In this spike-pattern code, the what and the when of the stimuli are encoded in the duration of each burst and the time of burst onset, respectively. Given the ubiquity of burst firing, we expect similar findings also for other neural systems.
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发表时间: 1997-05-01
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