A meta-analysis of cerebellar contributions to higher cognition from PET and fMRI studies.
A meta-analysis of cerebellar contributions to higher cognition from PET and fMRI studies.
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DOI：
10.1002/hbm.22194
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发表时间：
2014-02
影响因子：
4.8
通讯作者：
Desmond, John E.
中科院分区：
文献类型：
--
作者：
Keren-Happuch, E.;Chen, Shen-Hsing Annabel;Ho, Moon-Ho Ringo;Desmond, John E.
近年来，对小脑功能及其参与高级认知的兴趣日益浓厚，引发了许多研究。在越来越多的神经影像学文献中，已经观察到小脑在广泛的认知功能中的存在。我们应用了一种荟萃分析方法，采用激活似然估计方法，巩固小脑参与积累在不同的认知任务的兴趣和系统地确定研究之间的相似性的结果。目前的分析包括88项神经影像学研究，这些研究表明小脑在涉及情感、执行功能、语言、音乐、计时和工作记忆的高级认知领域中激活。虽然在很大程度上与之前的荟萃分析一致，但我们的结果扩展了他们的发现，包括音乐和时间域，以进一步了解小脑参与并阐明其在高级认知中的作用。此外，我们还对情绪、语言和工作记忆的认知领域进行了域间和域内比较。我们还考虑了任务的差异进行比较的斯滕贝格与n-back任务，以及分析的差异组件内的斯滕贝格任务的言语工作记忆的域。结果显示，小脑在计时域中一致存在，为计时作用提供了证据。在该领域内确定的独特集群进一步细化小脑的地形组织。
A growing interest in cerebellar function and its involvement in higher cognition have prompted much research in recent years. Cerebellar presence in a wide range of cognitive functions examined within an increasing body of neuroimaging literature has been observed. We applied a meta-analytic approach, which employed the activation likelihood estimate method, to consolidate results of cerebellar involvement accumulated in different cognitive tasks of interest and systematically identified similarities among the studies. The current analysis included 88 neuroimaging studies demonstrating cerebellar activations in higher cognitive domains involving emotion, executive function, language, music, timing and working memory. While largely consistent with a prior meta-analysis by, our results extended their findings to include music and timing domains to provide further insights into cerebellar involvement and elucidate its role in higher cognition. In addition, we conducted inter- and intra-domain comparisons for the cognitive domains of emotion, language and working memory. We also considered task differences within the domain of verbal working memory by conducting a comparison of the Sternberg with the n-back task, as well as an analysis of the differential components within the Sternberg task. Results showed a consistent cerebellar presence in the timing domain, providing evidence for a role in time keeping. Unique clusters identified within the domain further refine the topographic organization of the cerebellum.
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影响因子：
3.7
作者：
Chen, Joyce L.;Penhune, Virginia B.;Zatorre, Robert J.
通讯作者：
Zatorre, Robert J.
影响因子：
56.9
作者：
Allen, G;Buxton, RB;Courchesne, E
通讯作者：
Courchesne, E
DOI：
10.1016/j.cogbrainres.2004.06.014
发表时间：
2004-11-01
期刊：
COGNITIVE BRAIN RESEARCH
影响因子：
--
作者：
Cairo, TA;Liddle, PF;Ngan, ETC
通讯作者：
Ngan, ETC
影响因子：
14.5
作者：
Dagher, A;Owen, AM;Brooks, DJ
通讯作者：
Brooks, DJ
DOI：
10.1111/j.1749-6632.2002.tb07557.x
发表时间：
2002-01-01
期刊：
CREBELLUM: RECENT DEVELOPMENTS IN CEREBELLAR RESEARCH
影响因子：
--
作者：
Attwell, PJE;Ivarsson, M;Yeo, CH
通讯作者：
Yeo, CH