Medical Record Review to Differentiate between Idiopathic Parkinson's Disease and Parkinsonism: A Danish Record Linkage Study with 10 Years of Follow-Up.
Medical Record Review to Differentiate between Idiopathic Parkinson's Disease and Parkinsonism: A Danish Record Linkage Study with 10 Years of Follow-Up.
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医疗记录审查以区分特发性帕金森病和帕金森病：丹麦记录关联研究及 10 年随访。
DOI：
10.1155/2015/781479
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发表时间：
2015
期刊：
影响因子：
--
通讯作者：
Ritz,Beate
中科院分区：
文献类型：
--
作者：
Wermuth,Lene;Cui,Xin;Greene,Naomi;Schernhammer,Eva;Ritz,Beate
背景如果能够获得有效和可靠的诊断，电子病历为大规模基于人群的临床研究提供了前所未有的新机会，以确定需要哪些信息来区分电子病历中的特发性PD和帕金森症。对1996年至2009年间在丹麦国家医院登记处登记为特发性PD的出院诊断为PD的2，446例患者的完整病历进行了图表审查。所有患者均在神经内科进行检查。从图表中提取临床特征，以确定帕金森病的表型和病程，使用预先定义的特发性PD的标准。病历审查证实，2，068例（84.5%）患者符合特发性PD标准。特发性PD患者最显著的特征是不对称发作，与帕金森症相比，发作或随访时的非典型特征较少，单独这些项目的曲线下面积（AUC）为中度（0.74-0.77），当使用除PD药物使用和5年或更长时间随访外记录的所有临床特征时达到最高AUC（0.91）。为了减少疾病错误分类，从首次诊断后至少随访5年的病历审查中提取的信息是提高诊断准确性的关键。
Background. The electronic medical records provide new and unprecedented opportunities for large population‐based and clinical studies if valid and reliable diagnoses can be obtained, to determine what information is needed to distinguish idiopathic PD from Parkinsonism in electronic medical records.Methods. Chart review of complete medical records of 2,446 patients with a hospital discharge diagnosis of PD, who, between 1996 and 2009, were registered in the Danish National Hospital Register as idiopathic PD. All patients were examined in neurology departments. Clinical features were abstracted from charts to determine Parkinsonian phenotypes and disease course, using predefined criteria for idiopathic PD.Results. Chart review verified that 2,068 (84.5%) patients met criteria for idiopathic PD. The most distinguishing features of idiopathic PD patients were asymmetric onset, and fewer atypical features at onset or follow‐up compared to Parkinsonism, and the area under the curve (AUC) for these items alone is moderate (0.74–0.77) and the highest AUC (0.91) was achieved when using all clinical features recorded in addition to PD medication use and a follow‐up of 5 years or more.Conclusion. To reduce disease misclassification, information extracted from medical record review with at least 5 years of follow‐up after first diagnosis was key to improve diagnostic accuracy.
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在 Macintosh 计算机上使用数字化听觉刺激
DOI：
--
发表时间：
1987
期刊：
影响因子：
--
作者：
J. M. Gibson
通讯作者：
J. M. Gibson
DOI：
10.1037//0278-7393.9.1.21
发表时间：
1983
期刊：
Journal of experimental psychology. Learning, memory, and cognition
影响因子：
--
作者：
L. Jacoby
通讯作者：
L. Jacoby
提示贬值：当单词片段的完成因先前接触较小的片段而受到破坏时。
DOI：
10.1037//0278-7393.12.3.426
发表时间：
1986
期刊：
Journal of experimental psychology. Learning, memory, and cognition
影响因子：
--
作者：
Peynircioğlu,ZF;Watkins,MJ
通讯作者：
Watkins,MJ
DOI：
10.1037/h0080638
发表时间：
1982-01-01
期刊：
CANADIAN JOURNAL OF PSYCHOLOGY-REVUE CANADIENNE DE PSYCHOLOGIE
影响因子：
--
作者：
JACOBY, LL;WITHERSPOON, D
通讯作者：
WITHERSPOON, D
影响因子：
15
作者：
Leatherman, MD;Svejda, SA;Brookhart, M
通讯作者：
Brookhart, M