Elevated levels of protein carbonyls in sera of chronic fatigue syndrome patients
Elevated levels of protein carbonyls in sera of chronic fatigue syndrome patients
复制标题
慢性疲劳综合征患者血清中蛋白质羰基水平升高
DOI：
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发表时间：
2003
影响因子：
4.3
通讯作者：
M. Pall
中科院分区：
文献类型：
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作者：
Iva Smirnova;M. Pall
与对照组相比，慢性疲劳综合征 (CFS) 患者血清中的蛋白质羰基水平（蛋白质氧化的衡量标准）显着升高 (p < 0.0005)。相比之下，CFS 患者的血清总蛋白水平与对照组相比没有变化。蛋白质羰基水平升高证实了早期的报告，即氧化应激与慢性疲劳综合征相关，并且与慢性疲劳综合征和相关病症的一氧化氮/过氧亚硝酸盐升高理论的预测一致。
Protein carbonyl levels, a measure of protein oxidation, were found to be significantly elevated (p < 0.0005) in the sera of chronic fatigue syndrome (CFS) patients vs. controls. In contrast, the total protein levels in sera CFS patients were unchanged from those of controls. The elevated protein carbonyl levels confirm earlier reports suggesting that oxidative stress is associated with chronic fatigue syndrome and are consistent with a prediction of the elevated nitric oxide/peroxynitrite theory of chronic fatigue syndrome and related conditions.
慢性疲劳综合征中 37-kDa 2-5A 依赖性 RNase L 的结构和功能特征。
DOI：
10.1089/10799900252952235
发表时间：
2002
期刊：
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
影响因子：
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作者：
Shetzline,SusanE;Martinand-Mari,Camille;Reichenbach,NancyL;Buletic,Zivjena;Lebleu,Bernard;Pfleiderer,Wolfgang;Charubala,Ramamurthy;DeMeirleir,Kenny;DeBecker,Pascale;Peterson,DanielL;Herst,CVT;Englebienne,Patrick;Suhadolnik,
通讯作者：
Suhadolnik,