Characteristics associated with the perceived likelihood to become parents among young adults with sickle cell disease or sickle cell trait in the USA.
Characteristics associated with the perceived likelihood to become parents among young adults with sickle cell disease or sickle cell trait in the USA.
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DOI：
10.1002/jgc4.1535
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发表时间：
2022-06
影响因子：
1.9
通讯作者：
Wilkie, Diana J.
中科院分区：
文献类型：
--
作者：
Aldossary, Dalal S.;Black, Vandy;Ezenwa, Miriam O.;Gallo, Agatha M.;Johnson-Mallard, Versie M.;Eades, Nyema T.;Oguntoye, Anne O.;Yao, Yingwei;Wilkie, Diana J.
患有镰状细胞病（SCD）的个体和患有镰状细胞性状（SCT）的个体具有不同的健康轨迹，但尚不清楚社会人口统计学和临床特征是否与他们成为父母的可能性相关。本研究的目的是研究美国一组患有SCD或SCT的年轻成人中与感知的亲母可能性相关的社会人口统计学和临床特征。参与者是234名年轻人（82名男性，152名女性），他们患有SCD（n=138）或SCT（n=96）。平均年龄为25.9岁（SD=4.9），大多数参与者（87%）是单身。研究参与者完成了有效和可靠的镰状细胞生殖健康知识育儿意图和行为问卷（SCKnowIQ）中的父母可能性项目（0-4量表）。平均父母可能性得分为M=2.3（SD=1.1），41%的人表示他们“非常”或“非常”有可能成为父母。双变量分析显示，与父母的可能性与参与者的镰状细胞基因型（p= 0.03），年龄（p= 0.003），教育水平（p= 0.04），收入（p= 0.01），就业（p= 0.04），子女数量（p<0.001），健康保险（p= 0.02）以及其他因素（p<0.001）有关。在多元回归分析中，如果参与者最多有2个孩子（p=0.03），收入较高（p = 0.03），没有保险（p=0.01），并且受他人影响程度较高（p=0.001），则参与者报告的父母得分更高。需要更多的研究来证实这些发现在更大的代表性样本与更多的年轻成年男性，并了解可能成为父母随着时间的推移，通过实施纵向研究在SCD和SCT人群。这样的研究是必要的，以指导适当的教育和遗传咨询与SCD或SCT的年轻成年人的生殖决策。
Individuals with sickle cell disease (SCD) and individuals with sickle cell trait (SCT) have different health trajectories, but it is unknown if sociodemographic and clinical characteristics are associated with their likelihood to be a parent. The purpose of this study was to examine the sociodemographic and clinical characteristics associated with perceived likelihood-to-parent among a cohort of young adults with SCD or SCT in the United States. The participants were 234 young adults (82 males, 152 females) who had either SCD (n=138) or SCT (n=96). The average age was 25.9 years (SD=4.9), and most participants (87%) were single. Study participants completed the likelihood-to-parent item (0–4 scale) included in the valid and reliable Sickle Cell Reproductive Health Knowledge Parenting Intent and Behavior Questionnaire (SCKnowIQ). The mean likelihood-to-parent score was M=2.3 (SD=1.1) and 41% indicated that they were “very” or “extremely” likely to be a parent. Bivariate analysis showed that likelihood-to-parent was associated with the participant’s sickle cell genotype (p=.03), age (p=.003), educational level (p=.04), income (p=.01), employment (p=.04), number of children (p<.001), health insurance (p=.02), and influenced by others (p<.001). In multiple regression analysis, participants reported higher likelihood-to-parent scores if they had at most 2 children (p=0.03), higher income (p=0.03), had no insurance (p=0.01) and reported higher levels of being influenced by others (p=0.001). Additional research is needed to confirm these findings in larger representative samples with more young adult males and to understand the likelihood to become parents over time by implementing longitudinal studies in the SCD and SCT populations. Such research is needed to guide appropriate education and genetic counseling for reproductive decision-making among young adults with SCD or SCT.
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DOI：
10.1016/j.pedn.2008.07.010
发表时间：
2009-06-01
期刊：
Journal of pediatric nursing
影响因子：
--
作者：
Gallo, Agatha M;Knafl, Kathleen A;Angst, Denise B
通讯作者：
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影响因子：
1.8
作者：
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影响因子：
2.5
作者：
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通讯作者：
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影响因子：
1.4
作者：
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通讯作者：
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影响因子：
3.3
作者：
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通讯作者：
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