Advancing collaborations in health research and clinical trials in Sub-Saharan Africa: development and implementation of a biostatistical collaboration module in the Masters in Biostatistics Program at Stellenbosch University.
Advancing collaborations in health research and clinical trials in Sub-Saharan Africa: development and implementation of a biostatistical collaboration module in the Masters in Biostatistics Program at Stellenbosch University.
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DOI：
10.1186/s13063-021-05427-x
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发表时间：
2021-07-22
期刊：
影响因子：
2.5
通讯作者：
Thabane L
中科院分区：
文献类型：
--
作者：
Esterhuizen TM;Li G;Young T;Zeng J;Machekano R;Thabane L
撒哈拉以南非洲继续承受着结核病和艾滋病毒等传染病以及高血压和其他心血管疾病等非传染病的沉重负担。虽然对研究的投资导致了成果改善方面的进展，但在建设卫生研究能力方面仍有许多工作要做。与世界上许多其他地区一样，撒哈拉以南非洲地区严重缺乏生物统计学家和临床试验方法学家。通过Fogarty全球健康培训计划资助，南非斯泰伦博斯大学医学与健康科学学院于2017年1月启动了一项新的生物统计学硕士课程。在本文中，我们描述了一个生物统计学和临床试验合作模块的开发，改编自麦克马斯特大学健康研究方法学项目中提供的类似课程。该单元以三个核心原则（体验式学习、多学科/跨学科方法和正式导师制）为指导，旨在通过促进学习如何在实践中系统地应用基本统计和试验方法学知识，同时加强与其他医疗保健研究人员有效合作以解决健康问题所需的一些软技能，来提高学员的生物统计协作技能。我们还分享了2018年1月至11月至2021年参加该模块的前四个队列的一些初步发现。我们希望本模块可以提供一个如何改善生物统计和临床试验合作，并加快在低资源环境下的研究能力建设的例子。美国国立卫生研究院福格蒂国际中心。
Sub-Saharan Africa continues to carry a high burden of communicable diseases such as TB and HIV and non-communicable diseases such as hypertension and other cardiovascular conditions. Although investment in research has led to advances in improvements in outcomes, a lot still remains to be done to build research capacity in health. Like many other regions in the world, Sub-Saharan Africa suffers from a critical shortage of biostatisticians and clinical trial methodologists. Funded through a Fogarty Global Health Training Program grant, the Faculty of Medicine and Health Sciences at Stellenbosch University in South Africa established a new Masters Program in Biostatistics which was launched in January 2017. In this paper, we describe the development of a biostatistical and clinical trials collaboration Module, adapted from a similar course offered in the Health Research Methodology program at McMaster University. Guided by three core principles (experiential learning; multi-/inter-disciplinary approach; and formal mentorship), the Module aims to advance biostatistical collaboration skills of the trainees by facilitating learning in how to systematically apply fundamental statistical and trial methodological knowledge in practice while strengthening some soft skills which are necessary for effective collaborations with other healthcare researchers to solve health problems. We also share some preliminary findings from the first four cohorts that took the Module in January–November 2018 to 2021. We expect that this Module can provide an example of how to improve biostatistical and clinical trial collaborations and accelerate research capacity building in low-resource settings. Fogarty International Center of the National Institutes of Health.
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