Heterogeneity in Trajectories of Depression in Response to Divorce is Associated with Differential Risk for Mortality.
Heterogeneity in Trajectories of Depression in Response to Divorce is Associated with Differential Risk for Mortality.
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DOI：
10.1177/2167702617705951
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发表时间：
2017-09
期刊：
影响因子：
--
通讯作者：
Bonanno GA
中科院分区：
文献类型：
--
作者：
Malgaroli M;Galatzer-Levy IR;Bonanno GA
离婚是一种常见的压力事件，与抑郁症和死亡率的增加有关。鉴于主要生活压力源后抑郁症的显著个体差异的证据，我们研究了异质性抑郁反应是否赋予死亡率的差异风险。从人口为基础的纵向研究的数据被用来确定个人经历离婚（n=559）。从离婚前到离婚后的抑郁严重程度的前瞻性轨迹被确定为潜在增长混合模型，轨迹之间的死亡率作为远端结果进行比较。四个轨迹表现出最强的模型拟合：弹性（67%），紧急抑郁症（10%），慢性离婚前至离婚后抑郁症（12%）和抑郁症减少（11%）。事件发生后6年的死亡率为9.7%，与弹性（OR，2.46; 95%CI，1.05-5.81）和已婚个体相比，离婚导致的抑郁症与更大的死亡风险相关，而慢性抑郁症与更大的风险无关。
Divorce is a common stressful event associated with both increased rates of depression and mortality. Given evidence of significant individual differences in depression following major life stressors, we examined if heterogeneous depression responses confer differential risk for mortality. Data from a population based longitudinal study was utilized to identify individuals who experienced divorce (n=559). Prospective trajectories of depression severity from before to after divorce were identified using latent growth mixture modeling, and rates of mortality between trajectories were compared as a distal outcome. Four trajectories demonstrated strongest model fit: resilience (67%), emergent depression (10%), chronic pre-to-post divorce depression (12%), and decreasing depression (11%). Mortality base rate was 9.7% by 6 years post-event, and depression that emerged due to divorce was associated with significantly greater mortality risk compared to resilient (OR, 2.46; 95% CI, 1.05–5.81) and to married individuals, while chronic depression was not associated with greater risk.
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影响因子：
7
作者：
Egede, Leonard E.
通讯作者：
Egede, Leonard E.
影响因子：
8.2
作者：
Galatzer-Levy, Isaac R.;Bonanno, George A.
通讯作者：
Bonanno, George A.
影响因子：
4.2
作者：
Agrawal, Arpana;Lynskey, Michael T.
通讯作者：
Lynskey, Michael T.
DOI：
10.1146/annurev-clinpsy-032210-104526
发表时间：
2011-01-01
影响因子：
18.4
作者：
Bonanno, George A.;Westphal, Maren;Mancini, Anthony D.
通讯作者：
Mancini, Anthony D.
影响因子：
6.3
作者：
Eng, PM;Kawachi, I;Rimm, EB
通讯作者：
Rimm, EB