Effects of COVID-19 pandemic lockdown on gestational diabetes mellitus: A retrospective study.
Effects of COVID-19 pandemic lockdown on gestational diabetes mellitus: A retrospective study.
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DOI：
10.1016/j.diabet.2020.09.008
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发表时间：
2021-03
影响因子：
7.2
通讯作者：
Vambergue A
中科院分区：
文献类型：
--
作者：
Ghesquière L;Garabedian C;Drumez E;Lemaître M;Cazaubiel M;Bengler C;Vambergue A
本研究的目的是评估封锁期对GDM患者血糖平衡的影响。一项在一家中心（法国里尔）进行的回顾性研究比较了两个时期：2020年3月18日至2020年5月7日的COVID-19封锁与2019年同期。血糖目标定义为空腹毛细血管血糖目标<5.1 mmol/L和/或餐后2小时毛细血管血糖< 6.6 mmol/L。GDM控制定义为：良好（< 20%的血糖值不在目标范围内）、可接受（20 - 40%的血糖值不在目标范围内）或差（> 40%的血糖值不在目标范围内）。2019年纳入229例患者，2020年纳入222例患者。两组进行的毛细血管血糖检测的平均次数相同。2020年餐后血糖控制较好的比例明显降低，控制良好的比例较低（61.6%对69.4%），可接受的比例较高（24.7%对21.8%），控制不佳的比例较高（13.7%对8.7%）（p < 0.05）。与2019年相比，2020年胰岛素治疗的使用率显著增加（分别为47.7%和36.2%; p < 0.05）。在COVID-19大流行封锁期间，糖尿病控制率较低，即使随访没有受到影响。这可能是因为在此期间减少了体力活动，改变了饮食习惯和焦虑。
The objective of our study was to evaluate the impact of the lockdown period on the glycemic balance in patients with GDM. A retrospective study in one center (Lille, France) compared two periods: the COVID-19 lockdown of 18 March 2020 to 7 May 2020 versus the same period during 2019. Glucose targets were defined by a capillary fasting glucose target < 5.1mmol/L and/or a 2-hour postprandial capillary glucose < 6.6 mmol/L. GDM control was defined as: good (< 20% of the glycemic values were not within the target range), acceptable (20 to 40% of the glycemic values were not within the target range) or poor (> 40% of the glycemic values were not within the target range). Two hundred twenty-nine patients were included in 2019 and 222 in 2020. The same mean number of capillary blood sugar tests was performed by the two groups. Postprandial blood sugar was significantly less well controlled in 2020, with a lower rate of good control (61.6% vs 69.4%) and higher rates of acceptable (24.7% vs 21.8%) and poor control (13.7% and 8.7%) (p < 0.05). Use of insulin therapy was significantly higher in 2020 compared with 2019 (47.7% and 36.2%, respectively; p < 0.05). Diabetes control was lower during the COVID-19 pandemic lockdown, even if follow-up was not impacted. This may be explained by reduced physical activity, modified dietary habits and anxiety during this period.
影响因子：
4.2
作者：
Zhu Y;Zhang C
通讯作者：
Zhang C
影响因子：
3.6
作者：
Farewell, Charlotte V.;Jewell, Jennifer;Leiferman, Jenn A.
通讯作者：
Leiferman, Jenn A.
影响因子：
5.4
作者：
Murphy, Helen R.
通讯作者：
Murphy, Helen R.