Prevalence of Gestational Diabetes and Risk of Progression to Type 2 Diabetes: a Global Perspective.
Prevalence of Gestational Diabetes and Risk of Progression to Type 2 Diabetes: a Global Perspective.
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DOI：
10.1007/s11892-015-0699-x
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发表时间：
2016-01
影响因子：
4.2
通讯作者：
Zhang C
中科院分区：
文献类型：
--
作者：
Zhu Y;Zhang C
尽管糖尿病在不同生命阶段的人群中越来越流行，但妊娠期糖尿病（GDM）的全球负担尚未得到很好的评估。缺乏关于GDM全球流行率估计的系统综合数据，特别是在发展中国家。妊娠合并GDM的宫内高血糖环境可能不仅反映了2型糖尿病（T2DM）的流行，而且助长了它的流行。我们全面回顾了过去十年的现有数据，试图按国家和地区估计当前全球GDM的流行情况。我们也回顾了从GDM发展为T2DM的风险。综合数据表明，在GDM的患病率估计和从GDM进展为T2DM的风险方面存在很大差异。鉴于筛查方法、诊断标准和潜在人群特征的巨大异质性，直接比较不同国家或地区的GDM负担具有挑战性。在这方面，估算全球GDM患病率的合作努力将是一个巨大但重要的飞跃。在向卫生政策制定者和卫生保健提供者通报疾病负担以及在全球制定更有针对性和更有效的糖尿病预防和管理战略方面，这些努力可能具有重大的公共卫生影响。
Despite the increasing epidemic of diabetes mellitus affecting populations at different life stages, the global burden of gestational diabetes mellitus (GDM) is not well assessed. Systematically synthesized data on global prevalence estimates of GDM are lacking, particularly among developing countries. The hyperglycemic intrauterine environment as exemplified in pregnancies complicated by GDM might not only reflect but also fuel the epidemic of type 2 diabetes mellitus (T2DM). We comprehensively reviewed available data in the past decade in an attempt to estimate the contemporary global prevalence of GDM by country and region. We reviewed the risk of progression from GDM to T2DM as well. Synthesized data demonstrate wide variations in both prevalence estimates of GDM and the risk of progression from GDM to T2DM. Direct comparisons of GDM burden across countries or regions are challenging given the great heterogeneity in screening approaches, diagnostic criteria, and underlying population characteristics. In this regard, collaborative efforts to estimate global GDM prevalence would be a large but important leap forward. Such efforts may have substantial public health implications in terms of informing health policy makers and healthcare providers for disease burden and for developing more targeted and effective diabetes prevention and management strategies globally.
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影响因子：
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