Clinicopathological Characteristics and Prognosis of Ossifying Fibroma in the Jaws of Children: A Retrospective Study.
Clinicopathological Characteristics and Prognosis of Ossifying Fibroma in the Jaws of Children: A Retrospective Study.
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儿童颌骨骨化纤维瘤的临床病理特征及预后：回顾性研究
DOI：
10.7150/jca.21556
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发表时间：
2017
影响因子：
3.9
通讯作者：
Cai ZG
中科院分区：
文献类型：
--
作者：
Liu Y;Shan XF;Guo XS;Xie S;Cai ZG
背景技术背景：颌骨骨化性纤维瘤是一种儿童易复发的良性肿瘤，其治疗方法及预后至今仍存在争议。本研究旨在回顾儿童颌骨骨化性纤维瘤的临床病理特征、治疗和预后，并为临床决策提供建议。方法：对18岁以下颌骨骨化性纤维瘤患者进行回顾性研究。有完整的临床、病理和放射学记录的患者被纳入并随访。结果：初步检索到63例。筛选后，纳入50例患者进行一般信息分析，其中42例患者纳入复发分析。复发12例，复发率28.6%（12/42）。不同手术入路、不同X线边界的复发率差异有统计学意义。23例行游离组织移植修复，成功率为96%（22/23）。结论：不同X线表现和手术方式的复发率有显著差异。扩大切除和游离组织移植重建是一种可靠的方法，成功率为96%。
BACKGROUND: Ossifying fibroma in the jaws is a benign tumor and easily recurs in children, of which the treatment methods and prognosis still remain controversial. In this study, we aimed to review the clinicopathological characteristics, treatment, and prognosis of ossifying fibroma in the jaws of children, and offer recommendations for clinical decision-making. METHODS: A retrospective study was carried out on patients below the age of 18 years with ossifying fibroma in the jaws. Patients with complete clinical, pathological, and radiological records were included and followed-up. RESULTS: Sixty-three cases were collected with a preliminary search. After screening, fifty patients were included for general information analysis, of which forty-two patients were included in the recurrence analysis. Twelve patients showed a relapse, with a recurrence rate of 28.6% (12/42). The recurrence rates in cases with different surgical approaches and different X-ray boundaries were statistically different. Besides, twenty-three patients underwent reconstruction by free tissue grafting and the success rate was 96% (22/23). CONCLUSIONS: There was significant difference in the recurrence rates among different X-ray manifestations and surgical methods. An extended resection and reconstruction with free tissue grafting was a reliable method with a 96% success rate.
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影响因子：
1.9
作者：
Troulis, MJ;Williams, WB;Kaban, LB
通讯作者：
Kaban, LB
影响因子：
0.9
作者：
Lv, Mingming;Shen, Yi;Sun, Jian
通讯作者：
Sun, Jian
影响因子：
1.2
作者：
Phattarataratip, Ekarat;Pholjaroen, Chanajit;Tiranon, Prawwalee
通讯作者：
Tiranon, Prawwalee
影响因子：
--
作者：
da Silveira DT;Cardoso FO;E Silva BJ;E Alves Cardoso CA;Manzi FR
通讯作者：
Manzi FR
DOI：
10.1016/j.tripleo.2006.03.027
发表时间：
2006-11-01
期刊：
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
影响因子：
--
作者：
Espinosa, Sebastian A;Villanueva, Julio;Reyes, Daniel
通讯作者：
Reyes, Daniel