Susceptibility to air pollution effects on mortality in Seoul, Korea: a case-crossover analysis of individual-level effect modifiers.
Susceptibility to air pollution effects on mortality in Seoul, Korea: a case-crossover analysis of individual-level effect modifiers.
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DOI：
10.1038/jes.2012.6
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发表时间：
2012-05
影响因子：
4.5
通讯作者：
中科院分区：
文献类型：
--
作者：
Air pollution’s mortality effects may differ by subpopulation; however, few studies have investigated this issue in Asia. We investigated susceptibility to air pollutants on total, cardiovascular, and respiratory mortality in Seoul, Korea for the period 2000 – 2007. We applied time-stratified case-crossover analysis, which allows direct modeling of interaction terms, to estimate susceptibility based on sex, age, education, marital status, and occupation. An interquartile range increase in pollution was associated with odds ratios of 0.94 (95% confidence interval, 0.25 – 1.62), 2.27 (1.03–3.53), 1.94 (0.80 – 3.09), and 2.21 (1.00 – 3.43) for total mortality and 1.95 (0.64 – 3.27), 4.82 (2.18 – 7.54), 3.64 (1.46 – 5.87), and 4.32 (1.77 – 6.92) for cardiovascular mortality for PM10, nitrogen dioxide (NO2), sulfur dioxide (SO2), and carbon monoxide (CO), respectively. Ozone effect estimates were positive, but not statistically significant. Results indicate that some populations are more susceptible than others. For total or cardiovascular mortality, associations were higher for males, those 65 – 74 years, and those with no education or manual occupation for some pollutants. For example, the odds ratio for SO2 and cardiovascular mortality was 1.19 (1.03 – 1.37) times higher for those with manual occupations than professional occupations. Our findings provide evidence that some populations are more susceptible to the effects of air pollution than others, which has implications for public policy and risk assessment for susceptible subpopulations.
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影响因子：
10.4
作者：
O'Neill MS;Jerrett M;Kawachi I;Levy JI;Cohen AJ;Gouveia N;Wilkinson P;Fletcher T;Cifuentes L;Schwartz J;Workshop on Air Pollution and Socioeconomic Conditions
通讯作者：
Workshop on Air Pollution and Socioeconomic Conditions
影响因子：
6.3
作者：
Jerrett, M;Burnett, RT;Hutchison, B
通讯作者：
Hutchison, B
影响因子：
5.4
作者：
Levy, D;Lumley, T;Checkoway, H
通讯作者：
Checkoway, H
影响因子：
5.4
作者：
Forastiere, Francesco;Stafoggia, Massimo;Perucci, Carlo A.
通讯作者：
Perucci, Carlo A.
影响因子：
10.4
作者：
Clougherty JE
通讯作者：
Clougherty JE