Virtual intracranial EEG signals reconstructed from MEG with potential for epilepsy surgery.
Virtual intracranial EEG signals reconstructed from MEG with potential for epilepsy surgery.
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DOI:
10.1038/s41467-022-28640-x
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发表时间:
2022-02-22
影响因子:
16.6
通讯作者:
Cook MJ
中科院分区:
文献类型:
--
作者:
Cao M;Galvis D;Vogrin SJ;Woods WP;Vogrin S;Wang F;Woldman W;Terry JR;Peterson A;Plummer C;Cook MJ
Modelling the interactions that arise from neural dynamics in seizure genesis is challenging but important in the effort to improve the success of epilepsy surgery. Dynamical network models developed from physiological evidence offer insights into rapidly evolving brain networks in the epileptic seizure. A limitation of previous studies in this field is the dependence on invasive cortical recordings with constrained spatial sampling of brain regions that might be involved in seizure dynamics. Here, we propose virtual intracranial electroencephalography (ViEEG), which combines non-invasive ictal magnetoencephalographic imaging (MEG), dynamical network models and a virtual resection technique. In this proof-of-concept study, we show that ViEEG signals reconstructed from MEG alone preserve critical temporospatial characteristics for dynamical approaches to identify brain areas involved in seizure generation. We show the non-invasive ViEEG approach may have some advantage over intracranial electroencephalography (iEEG). Future work may be designed to test the potential of the virtual iEEG approach for use in surgical management of epilepsy. Dynamic network models offer insight into brain networks affected by epileptic seizures. Here the authors derive ViEEG (virtual intracranial EEG) from non-invasive MEG recordings that show brain areas involved in seizure generation in patients with epilepsy.
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DOI:
10.1016/s1474-4422(15)00383-x
发表时间:
2016-04
期刊:
The Lancet. Neurology
影响因子:
--
作者:
Duncan JS;Winston GP;Koepp MJ;Ourselin S
通讯作者:
Ourselin S
影响因子:
7.8
作者:
Breakspear, M;Terry, JR;Friston, KJ
通讯作者:
Friston, KJ
影响因子:
5.7
作者:
Ding, Lei;Worrell, Gregory A.;He, Bin
通讯作者:
He, Bin
影响因子:
2.9
作者:
Junges, Leandro;Woldman, Wessel;Terry, John R.
通讯作者:
Terry, John R.
影响因子:
3.7
作者:
Breakspear, M.;Roberts, J. A.;Robinson, P. A.
通讯作者:
Robinson, P. A.