On Ice: The impact of vitrification on the use of eggs in fertility treatment.

On Ice: The impact of vitrification on the use of eggs in fertility treatment.
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On Ice:玻璃化冷冻对卵子在生育治疗中的使用的影响。

DOI:
10.1042/etls20190062
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发表时间:
2019
影响因子:
3.8
通讯作者:
Baldwin K
Baldwin K
中科院分区:
--
文献类型:
--
作者:
Baldwin K

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长期以来,由于疾病或药物治疗而面临不育的男性和女性都可以冷冻精子和胚胎。然而,成功冷冻保存人类卵子的能力相对较新。从2000年代中期开始,卵子玻璃化冷冻的引入和越来越多的使用,以及胞浆内单精子注射的使用,与缓慢冷冻方法相比,已经提高了持续的临床妊娠率。尽管存在关切,但这项技术已被科学界广泛接受,近年来已被应用于各种各样的环境。在这篇简短的观点论文中,我们考虑了常规辅助生殖实践中人类卵子玻璃化冷冻的两个具体应用:社会卵子冷冻和卵子捐赠中冷冻卵子的使用。我们认为,玻璃化正在以新颖而复杂的方式改变生殖景观,我们必须警惕这种发展的挑战,复杂性和道德,特别是对于那些可能被这些技术排除或边缘化的人。
The possibility to freeze sperm and embryos has long been available to men and women facing infertility as a result of an illness or medical treatment. However, the ability to successfully cryopreserve human eggs is comparatively recent. The introduction and increasing use of egg vitrification from the mid-2000s onwards, alongside the use of intracytoplasmic sperm injection, has seen improved ongoing clinical pregnancy rates compared with slow freezing methods. Despite concerns, the technology has been widely embraced by the scientific community and in recent years has been applied in a greater variety of contexts. In this short perspective paper, we consider two specific applications for the vitrification of human eggs in routine assisted reproduction practice: social egg freezing and the use of frozen eggs in egg donation. We suggest that vitrification is transforming the reproductive landscape in novel and complex ways and that we must be alert to the challenges, complexities and ethics of such developments, especially for those who may be excluded or marginalised by these techniques.
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DOI: --
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